Prehospital epinephrine overdose in a child resulting in ventricular dysrhythmias and myocardial ischemia

Colleen O. Davis, Paul M. Wax

Research output: Contribution to journalArticle

26 Scopus citations


Introduction: Epinephrine overdoses in children have been associated with supraventricular tachycardia. Myocardial ischemia subsequent to epinephrine overdose has not been reported in pediatric patients. Case report: We report a case of ventricular dysrhythmias and myocardial ischemia in a 5-year-old boy who received 10 times the recommended dose of subcutaneous epinephrine. Prehospital providers administered the epinephrine, believing it was part of a 'high-dose' epinephrine protocol. Discussion: There is no role for high-dose epinephrine in the treatment of allergic reactions or asthma. Careful epinephrine dosing, using mg/kg and verifying the volume, dilution, and route of administration is essential to prevent epinephrine toxicity.

Original languageEnglish (US)
Pages (from-to)116-118
Number of pages3
JournalPediatric emergency care
Issue number2
StatePublished - Apr 1999



  • Epinephrine
  • Myocardial ischemia
  • Pediatric overdose
  • Prehospital overdose
  • Ventricular dysrhythmias

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

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