Abstract
Preliminary biochemical investigations of differentiating cardiac muscle first revealed the occurrence of a third class of filaments, differing in appearance and reactivities from the thick and thin filaments of the sarcomere. These intermediate filaments were more resistant to extraction with neutral salts, β-mer-captoethanol, and urea than were the thick filaments, thin filaments, or Z material. Combined with the data from the accompanying report, sufficient evidence is presented to discount virtually all previous models of myofibrillogenesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 399-407 |
| Number of pages | 9 |
| Journal | Journal of Ultrasructure Research |
| Volume | 33 |
| Issue number | 5-6 |
| DOIs | |
| State | Published - Dec 1970 |
ASJC Scopus subject areas
- Anatomy
- Molecular Biology
Fingerprint Dive into the research topics of 'Preliminary biochemical investigations of the intermediate filaments'. Together they form a unique fingerprint.
Cite this
Rash, J. E., Shay, J. W., & Biesele, J. J. (1970). Preliminary biochemical investigations of the intermediate filaments. Journal of Ultrasructure Research, 33(5-6), 399-407. https://doi.org/10.1016/S0022-5320(70)90170-X