Preliminary single center north american experience with the berlin heart pediatric EXCOR device

Stephanie R. Rockett, Janet C. Bryant, W. Robert Morrow, Elizabeth A. Frazier, William P. Fiser, Wesley A. McKamie, Charles E. Johnson, Carl W. Chipman, Michiaki Imamura, Robert D B Jaquiss

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

For children requiring mechanical circulatory support as a bridge to cardiac transplantation in North America, options previously were limited to extracorporeal membrane oxygenation (ECMO) or centrifugal pump ventricular assist, both of which were suitable for only very short term application and were associated with significant complications and limitations. The Berlin Heart EXCOR ventricular assist device (VAD) was recently introduced into practice in North America to address this deficiency. We report a preliminary single center experience with the EXCOR in 17 children, 13 who received only a left-sided pump and four who required biventricular support. Before EXCOR placement, six patients were on ECMO, and one was on a centrifugal VAD. Eleven children were bridged to transplantation, one was bridged to recovery, and one remains on support. Three children died during support and one died after explantation. There was one late death nearly 2 years after transplant. Complications included stroke in seven patients, two of which were ultimately fatal. Five patients required re-operations for bleeding or evacuation of hematoma. Despite a disappointing rate of neurologic morbidity, our preliminary experience with the EXCOR has been very encouraging.

Original languageEnglish (US)
Pages (from-to)479-482
Number of pages4
JournalASAIO Journal
Volume54
Issue number5
DOIs
StatePublished - Sep 1 2008

Fingerprint

Pediatrics
Oxygenation
Berlin
Membranes
Equipment and Supplies
Transplants
Extracorporeal Membrane Oxygenation
Heart-Assist Devices
Centrifugal pumps
North America
Pumps
Recovery
Heart Transplantation
Hematoma
Nervous System
Transplantation
Stroke
Hemorrhage
Morbidity

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering
  • Medicine(all)

Cite this

Rockett, S. R., Bryant, J. C., Morrow, W. R., Frazier, E. A., Fiser, W. P., McKamie, W. A., ... Jaquiss, R. D. B. (2008). Preliminary single center north american experience with the berlin heart pediatric EXCOR device. ASAIO Journal, 54(5), 479-482. https://doi.org/10.1097/MAT.0b013e318184e200

Preliminary single center north american experience with the berlin heart pediatric EXCOR device. / Rockett, Stephanie R.; Bryant, Janet C.; Morrow, W. Robert; Frazier, Elizabeth A.; Fiser, William P.; McKamie, Wesley A.; Johnson, Charles E.; Chipman, Carl W.; Imamura, Michiaki; Jaquiss, Robert D B.

In: ASAIO Journal, Vol. 54, No. 5, 01.09.2008, p. 479-482.

Research output: Contribution to journalArticle

Rockett, SR, Bryant, JC, Morrow, WR, Frazier, EA, Fiser, WP, McKamie, WA, Johnson, CE, Chipman, CW, Imamura, M & Jaquiss, RDB 2008, 'Preliminary single center north american experience with the berlin heart pediatric EXCOR device', ASAIO Journal, vol. 54, no. 5, pp. 479-482. https://doi.org/10.1097/MAT.0b013e318184e200
Rockett SR, Bryant JC, Morrow WR, Frazier EA, Fiser WP, McKamie WA et al. Preliminary single center north american experience with the berlin heart pediatric EXCOR device. ASAIO Journal. 2008 Sep 1;54(5):479-482. https://doi.org/10.1097/MAT.0b013e318184e200
Rockett, Stephanie R. ; Bryant, Janet C. ; Morrow, W. Robert ; Frazier, Elizabeth A. ; Fiser, William P. ; McKamie, Wesley A. ; Johnson, Charles E. ; Chipman, Carl W. ; Imamura, Michiaki ; Jaquiss, Robert D B. / Preliminary single center north american experience with the berlin heart pediatric EXCOR device. In: ASAIO Journal. 2008 ; Vol. 54, No. 5. pp. 479-482.
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