Preoperative radioactive seed localization for nonpalpable breast lesions: Technique, pitfalls, and solutions

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Iodine 125 (<sup>125</sup>I) radioactive seed localization has emerged as a reliable and safe alternative to wire localization for guidance during the surgical resection of nonpalpable breast lesions. The breast imager has a responsibility to be familiar with the general principles of this evolving technique, including its advantages and disadvantages as well as the technical differences involved in placement of seeds versus traditional wire localization. Although placement of 125I seeds is conceptually similar to wire placement, there are additional technical considerations and safety measures that need to be addressed and implemented when radioactive seeds are used. We draw from our experience with more than 1000 cases of radioactive seed localization since inception of our program in 2009 to provide illustrative examples of not only the proper technique of radioactive seed localization, but also mishaps that may occur during this procedure, along with practical suggestions to prevent these problems. We examine some of the difficulties that we have encountered during radioactive seed localization at our institution, including bone wax mimicking the seed, the inadvertent deployment of seeds, the need for multiple seeds or supplemental wires, problematic seed locations, and difficulty in surgical retrieval of the seed. Recognizing the potential pitfalls of radioactive seed localization and understanding the appropriate guidelines and precautions for the safe, secure handling and placement of radioactive seeds is essential for a successful radioactive seed localization program.

Original languageEnglish (US)
Pages (from-to)1319-1334
Number of pages16
JournalRadiographics
Volume35
Issue number5
DOIs
StatePublished - Sep 1 2015

Fingerprint

Seeds
Breast
Iodine
Guidelines
Safety

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Preoperative radioactive seed localization for nonpalpable breast lesions : Technique, pitfalls, and solutions. / Goudreau, Sally H.; Joseph, Jamie P.; Seiler, Stephen J.

In: Radiographics, Vol. 35, No. 5, 01.09.2015, p. 1319-1334.

Research output: Contribution to journalArticle

@article{aaf3f38711a845278ef2ff2bf9224c69,
title = "Preoperative radioactive seed localization for nonpalpable breast lesions: Technique, pitfalls, and solutions",
abstract = "Iodine 125 (125I) radioactive seed localization has emerged as a reliable and safe alternative to wire localization for guidance during the surgical resection of nonpalpable breast lesions. The breast imager has a responsibility to be familiar with the general principles of this evolving technique, including its advantages and disadvantages as well as the technical differences involved in placement of seeds versus traditional wire localization. Although placement of 125I seeds is conceptually similar to wire placement, there are additional technical considerations and safety measures that need to be addressed and implemented when radioactive seeds are used. We draw from our experience with more than 1000 cases of radioactive seed localization since inception of our program in 2009 to provide illustrative examples of not only the proper technique of radioactive seed localization, but also mishaps that may occur during this procedure, along with practical suggestions to prevent these problems. We examine some of the difficulties that we have encountered during radioactive seed localization at our institution, including bone wax mimicking the seed, the inadvertent deployment of seeds, the need for multiple seeds or supplemental wires, problematic seed locations, and difficulty in surgical retrieval of the seed. Recognizing the potential pitfalls of radioactive seed localization and understanding the appropriate guidelines and precautions for the safe, secure handling and placement of radioactive seeds is essential for a successful radioactive seed localization program.",
author = "Goudreau, {Sally H.} and Joseph, {Jamie P.} and Seiler, {Stephen J.}",
year = "2015",
month = "9",
day = "1",
doi = "10.1148/rg.2015140293",
language = "English (US)",
volume = "35",
pages = "1319--1334",
journal = "Radiographics",
issn = "0271-5333",
publisher = "Radiological Society of North America Inc.",
number = "5",

}

TY - JOUR

T1 - Preoperative radioactive seed localization for nonpalpable breast lesions

T2 - Technique, pitfalls, and solutions

AU - Goudreau, Sally H.

AU - Joseph, Jamie P.

AU - Seiler, Stephen J.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Iodine 125 (125I) radioactive seed localization has emerged as a reliable and safe alternative to wire localization for guidance during the surgical resection of nonpalpable breast lesions. The breast imager has a responsibility to be familiar with the general principles of this evolving technique, including its advantages and disadvantages as well as the technical differences involved in placement of seeds versus traditional wire localization. Although placement of 125I seeds is conceptually similar to wire placement, there are additional technical considerations and safety measures that need to be addressed and implemented when radioactive seeds are used. We draw from our experience with more than 1000 cases of radioactive seed localization since inception of our program in 2009 to provide illustrative examples of not only the proper technique of radioactive seed localization, but also mishaps that may occur during this procedure, along with practical suggestions to prevent these problems. We examine some of the difficulties that we have encountered during radioactive seed localization at our institution, including bone wax mimicking the seed, the inadvertent deployment of seeds, the need for multiple seeds or supplemental wires, problematic seed locations, and difficulty in surgical retrieval of the seed. Recognizing the potential pitfalls of radioactive seed localization and understanding the appropriate guidelines and precautions for the safe, secure handling and placement of radioactive seeds is essential for a successful radioactive seed localization program.

AB - Iodine 125 (125I) radioactive seed localization has emerged as a reliable and safe alternative to wire localization for guidance during the surgical resection of nonpalpable breast lesions. The breast imager has a responsibility to be familiar with the general principles of this evolving technique, including its advantages and disadvantages as well as the technical differences involved in placement of seeds versus traditional wire localization. Although placement of 125I seeds is conceptually similar to wire placement, there are additional technical considerations and safety measures that need to be addressed and implemented when radioactive seeds are used. We draw from our experience with more than 1000 cases of radioactive seed localization since inception of our program in 2009 to provide illustrative examples of not only the proper technique of radioactive seed localization, but also mishaps that may occur during this procedure, along with practical suggestions to prevent these problems. We examine some of the difficulties that we have encountered during radioactive seed localization at our institution, including bone wax mimicking the seed, the inadvertent deployment of seeds, the need for multiple seeds or supplemental wires, problematic seed locations, and difficulty in surgical retrieval of the seed. Recognizing the potential pitfalls of radioactive seed localization and understanding the appropriate guidelines and precautions for the safe, secure handling and placement of radioactive seeds is essential for a successful radioactive seed localization program.

UR - http://www.scopus.com/inward/record.url?scp=84941630899&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941630899&partnerID=8YFLogxK

U2 - 10.1148/rg.2015140293

DO - 10.1148/rg.2015140293

M3 - Article

C2 - 26274097

AN - SCOPUS:84941630899

VL - 35

SP - 1319

EP - 1334

JO - Radiographics

JF - Radiographics

SN - 0271-5333

IS - 5

ER -