Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism

Cletus A. Arciero, S. Zita Shiue, Jeremy D. Gates, George E. Peoples, Alan P B Dackiw, Ralph P. Tufano, Steven K. Libutti, Martha A. Zeiger, Alexander Stojadinovic

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalJournal of Cancer
Issue number1
StatePublished - 2012


  • Hyperparathyroidism
  • Surgery
  • Thyroid
  • Thyroid cancer
  • Ultrasound

ASJC Scopus subject areas

  • Oncology


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