Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism

Cletus A. Arciero, S. Zita Shiue, Jeremy D. Gates, George E. Peoples, Alan P B Dackiw, Ralph P. Tufano, Steven K. Libutti, Martha A. Zeiger, Alexander Stojadinovic

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalJournal of Cancer
Volume3
Issue number1
DOIs
StatePublished - 2012

Fingerprint

Primary Hyperparathyroidism
Thyroid Gland
Pathology
Ultrasonography
Technetium Tc 99m Sestamibi
Thyroid Nodule
Research Ethics Committees
Thyroidectomy
Fine Needle Biopsy
Thyroid Neoplasms
Decision Making
Demography
Prospective Studies

Keywords

  • Hyperparathyroidism
  • Surgery
  • Thyroid
  • Thyroid cancer
  • Ultrasound

ASJC Scopus subject areas

  • Oncology

Cite this

Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism. / Arciero, Cletus A.; Shiue, S. Zita; Gates, Jeremy D.; Peoples, George E.; Dackiw, Alan P B; Tufano, Ralph P.; Libutti, Steven K.; Zeiger, Martha A.; Stojadinovic, Alexander.

In: Journal of Cancer, Vol. 3, No. 1, 2012, p. 1-6.

Research output: Contribution to journalArticle

Arciero, CA, Shiue, SZ, Gates, JD, Peoples, GE, Dackiw, APB, Tufano, RP, Libutti, SK, Zeiger, MA & Stojadinovic, A 2012, 'Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism', Journal of Cancer, vol. 3, no. 1, pp. 1-6. https://doi.org/10.7150/jca.3.1
Arciero, Cletus A. ; Shiue, S. Zita ; Gates, Jeremy D. ; Peoples, George E. ; Dackiw, Alan P B ; Tufano, Ralph P. ; Libutti, Steven K. ; Zeiger, Martha A. ; Stojadinovic, Alexander. / Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism. In: Journal of Cancer. 2012 ; Vol. 3, No. 1. pp. 1-6.
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AU - Dackiw, Alan P B

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AB - Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

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