Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene.

L. F. Parada, R. A. Weinberg

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro exposure to the carcinogen 3-methylcholanthrene. These oncogenes are now shown to be versions of the cellular Kirsten ras gene and are therefore homologous to oncogenes detected in a variety of human tumor DNAs.

Original languageEnglish (US)
Pages (from-to)2298-2301
Number of pages4
JournalMolecular and Cellular Biology
Volume3
Issue number12
StatePublished - Dec 1983

Fingerprint

Kirsten murine sarcoma virus
Methylcholanthrene
ras Genes
Oncogenes
DNA
Carcinogens
Fibroblasts
Neoplasms

ASJC Scopus subject areas

  • Cell Biology
  • Genetics
  • Molecular Biology

Cite this

Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. / Parada, L. F.; Weinberg, R. A.

In: Molecular and Cellular Biology, Vol. 3, No. 12, 12.1983, p. 2298-2301.

Research output: Contribution to journalArticle

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