Presynaptic Unsilencing: Searching for a Mechanism

Deniz Atasoy; Ege T. Kavalali

doi:10.1016/j.neuron.2006.04.018

Presynaptic Unsilencing: Searching for a Mechanism

Deniz Atasoy, Ege T. Kavalali

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.

Original language	English (US)
Pages (from-to)	345-346
Number of pages	2
Journal	Neuron
Volume	50
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2006.04.018
State	Published - May 4 2006

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2006.04.018

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title = "Presynaptic Unsilencing: Searching for a Mechanism",

abstract = "Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.",

author = "Deniz Atasoy and Kavalali, {Ege T.}",

year = "2006",

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AU - Atasoy, Deniz

AU - Kavalali, Ege T.

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AB - Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.

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VL - 50

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JO - Neuron

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Presynaptic Unsilencing: Searching for a Mechanism

Abstract

ASJC Scopus subject areas

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