Presynaptic Unsilencing: Searching for a Mechanism

Deniz Atasoy, Ege T. Kavalali

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.

Original languageEnglish (US)
Pages (from-to)345-346
Number of pages2
JournalNeuron
Volume50
Issue number3
DOIs
StatePublished - May 4 2006

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Synapses
Monomeric GTP-Binding Proteins
Synaptic Vesicles
Brain-Derived Neurotrophic Factor
Action Potentials
Actins
Neurons
Incidence

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Presynaptic Unsilencing : Searching for a Mechanism. / Atasoy, Deniz; Kavalali, Ege T.

In: Neuron, Vol. 50, No. 3, 04.05.2006, p. 345-346.

Research output: Contribution to journalArticle

Atasoy, Deniz ; Kavalali, Ege T. / Presynaptic Unsilencing : Searching for a Mechanism. In: Neuron. 2006 ; Vol. 50, No. 3. pp. 345-346.
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