Prevalence of left ventricular hypertrophy in persons with and without obstructive sleep apnea

Rishi Sukhija, Wilbert S. Aronow, Rasham Sandhu, Priyanka Kakar, George P. Maguire, Chul Ahn, Stuart G. Lehrman

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21 Scopus citations

Abstract

We investigated the prevalence of left ventricular hypertrophy (LVH) in persons with and without obstructive sleep apnea (OSA). Fifty-three persons had a nocturnal polysomnogram to diagnose OSA and 2-dimensional echocardiograms to measure left ventricular mass. OSA was considered mild if the respiratory disturbance index (RDI) was 5 to 15, moderate if the RDI was 15 to 30, and severe if the RDI was >30. LVH was diagnosed if the left ventricular mass index was >110 g/m in women and >134 g/m in men. LVH was present in 21 of 27 persons (78%) with moderate or severe OSA, in 6 of 13 persons (46%) with mild OSA, and in 3 of 13 persons (23%) with no OSA (P < 0.001 comparing moderate or severe OSA with no OSA and P < 0.05 comparing moderate or severe OSA with mild OSA). OSA was a significant independent predictor of LVH after controlling the confounding effects of hypertension with an odds ratio of 3.579 (95% confidence interval, 1.589-8.058).

Original languageEnglish (US)
Pages (from-to)170-172
Number of pages3
JournalCardiology in Review
Volume14
Issue number4
DOIs
Publication statusPublished - Jul 2006

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Keywords

  • Echocardiography
  • Left ventricular hypertrophy
  • Obstructive sleep apnea
  • Polysomnography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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