Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome

Shivani Patel, Linda M. Randolph, Kurt Benirschke, Arlyn Llanes, Larisa Yedigarova, Ramen H. Chmait

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives - Compared to singleton pregnancies, monochorionic twins have increased rates of perinatal morbidity and mortality, believed due in part to both twin-twin transfusion syndrome and an increased risk of congenital anomalies. Here we describe the prevalence of noncardiac structural anomalies in monochorionic twins with twin-twin transfusion syndrome who underwent laser surgery. Methods - In a retrospective study of 221 consecutive cases of twin-twin transfusion syndrome treated with laser surgery, noncardiac anomalies were identified by review of antepartum and neonatal medical records. Results - Of 377 live-born twins, 19 (5.0%) had a noncardiac anomaly. This rate was increased for donor versus recipient twins (8.5% versus 2.0%; P< .01). The presence of an anomaly was unrelated to the Quintero stage, the presence of donor intrauterine growth restriction, or 30-day survival of the donor or recipient. Conclusions - The prevalence of noncardiac anomalies in pregnancies complicated by twin-twin transfusion syndrome who underwent laser surgery was higher in donors versus recipients.

Original languageEnglish (US)
Pages (from-to)555-560
Number of pages6
JournalJournal of Ultrasound in Medicine
Volume31
Issue number4
StatePublished - Apr 1 2012

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Fetofetal Transfusion
Laser Therapy
Twin Pregnancy
Perinatal Mortality
Medical Records
Retrospective Studies
Morbidity
Pregnancy
Growth

Keywords

  • Congenital anomaly
  • Monochorionic twins
  • Twin-twin transfusion syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

Cite this

Patel, S., Randolph, L. M., Benirschke, K., Llanes, A., Yedigarova, L., & Chmait, R. H. (2012). Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome. Journal of Ultrasound in Medicine, 31(4), 555-560.

Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome. / Patel, Shivani; Randolph, Linda M.; Benirschke, Kurt; Llanes, Arlyn; Yedigarova, Larisa; Chmait, Ramen H.

In: Journal of Ultrasound in Medicine, Vol. 31, No. 4, 01.04.2012, p. 555-560.

Research output: Contribution to journalArticle

Patel, S, Randolph, LM, Benirschke, K, Llanes, A, Yedigarova, L & Chmait, RH 2012, 'Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome', Journal of Ultrasound in Medicine, vol. 31, no. 4, pp. 555-560.
Patel S, Randolph LM, Benirschke K, Llanes A, Yedigarova L, Chmait RH. Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome. Journal of Ultrasound in Medicine. 2012 Apr 1;31(4):555-560.
Patel, Shivani ; Randolph, Linda M. ; Benirschke, Kurt ; Llanes, Arlyn ; Yedigarova, Larisa ; Chmait, Ramen H. / Prevalence of noncardiac structural anomalies in twin-twin transfusion syndrome. In: Journal of Ultrasound in Medicine. 2012 ; Vol. 31, No. 4. pp. 555-560.
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AU - Chmait, Ramen H.

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