Preventing severe hypoxia during emergent intubation

Is nasopharyngeal oxygenation the answer?

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Critically ill patients requiring emergent endotracheal intubation are at risk for life-threatening hypoxemia during the intubation procedure, particularly when the patient is apneic and not receiving any supplemental oxygen. In a current study, Engström and colleagues investigated the effect of nasopharyngeal oxygenation in eight anesthetized pigs with induced acute lung injury. The investigators confirmed, even in this model, that pharyngeal oxygenation significantly prolonged the time to desaturation during periods of apnea. Recognizing the limitations of directly extrapolating these experimental results to critically ill human subjects, the findings do support the contention that, until proven otherwise, nasopharyngeal oxygenation should at least be considered as one technique to diminish hypoxemic complications in very sick patients, particularly those with underlying pulmonary impairment.

Original languageEnglish (US)
Article number1005
JournalCritical Care
Volume14
Issue number6
DOIs
StatePublished - Nov 3 2010

Fingerprint

Intubation
Critical Illness
Intratracheal Intubation
Acute Lung Injury
Apnea
Swine
Research Personnel
Oxygen
Lung
Hypoxia

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Medicine(all)

Cite this

@article{c64e597def534d18886453e0f78d0b40,
title = "Preventing severe hypoxia during emergent intubation: Is nasopharyngeal oxygenation the answer?",
abstract = "Critically ill patients requiring emergent endotracheal intubation are at risk for life-threatening hypoxemia during the intubation procedure, particularly when the patient is apneic and not receiving any supplemental oxygen. In a current study, Engstr{\"o}m and colleagues investigated the effect of nasopharyngeal oxygenation in eight anesthetized pigs with induced acute lung injury. The investigators confirmed, even in this model, that pharyngeal oxygenation significantly prolonged the time to desaturation during periods of apnea. Recognizing the limitations of directly extrapolating these experimental results to critically ill human subjects, the findings do support the contention that, until proven otherwise, nasopharyngeal oxygenation should at least be considered as one technique to diminish hypoxemic complications in very sick patients, particularly those with underlying pulmonary impairment.",
author = "Roppolo, {Lynn P.} and Wigginton, {Jane G.}",
year = "2010",
month = "11",
day = "3",
doi = "10.1186/cc9197",
language = "English (US)",
volume = "14",
journal = "Critical Care",
issn = "1466-609X",
publisher = "Springer Science + Business Media",
number = "6",

}

TY - JOUR

T1 - Preventing severe hypoxia during emergent intubation

T2 - Is nasopharyngeal oxygenation the answer?

AU - Roppolo, Lynn P.

AU - Wigginton, Jane G.

PY - 2010/11/3

Y1 - 2010/11/3

N2 - Critically ill patients requiring emergent endotracheal intubation are at risk for life-threatening hypoxemia during the intubation procedure, particularly when the patient is apneic and not receiving any supplemental oxygen. In a current study, Engström and colleagues investigated the effect of nasopharyngeal oxygenation in eight anesthetized pigs with induced acute lung injury. The investigators confirmed, even in this model, that pharyngeal oxygenation significantly prolonged the time to desaturation during periods of apnea. Recognizing the limitations of directly extrapolating these experimental results to critically ill human subjects, the findings do support the contention that, until proven otherwise, nasopharyngeal oxygenation should at least be considered as one technique to diminish hypoxemic complications in very sick patients, particularly those with underlying pulmonary impairment.

AB - Critically ill patients requiring emergent endotracheal intubation are at risk for life-threatening hypoxemia during the intubation procedure, particularly when the patient is apneic and not receiving any supplemental oxygen. In a current study, Engström and colleagues investigated the effect of nasopharyngeal oxygenation in eight anesthetized pigs with induced acute lung injury. The investigators confirmed, even in this model, that pharyngeal oxygenation significantly prolonged the time to desaturation during periods of apnea. Recognizing the limitations of directly extrapolating these experimental results to critically ill human subjects, the findings do support the contention that, until proven otherwise, nasopharyngeal oxygenation should at least be considered as one technique to diminish hypoxemic complications in very sick patients, particularly those with underlying pulmonary impairment.

UR - http://www.scopus.com/inward/record.url?scp=82155163817&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82155163817&partnerID=8YFLogxK

U2 - 10.1186/cc9197

DO - 10.1186/cc9197

M3 - Article

VL - 14

JO - Critical Care

JF - Critical Care

SN - 1466-609X

IS - 6

M1 - 1005

ER -