Prevention and Therapy of Steroid-Induced Diabetes

Iona Chapman, Arturo R. Dominguez, Amit G. Pandya

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Glucocorticoids are a common cause of medication-induced diabetes mellitus (DM). Practitioners caring for patients with autoimmune blistering disease (AIBD) should be aware of this complication as glucocorticoids, more often than not, are the initial treatment for most patients with AIBD. Failure to treat glucocorticoid-induced diabetes may result in neuropathy, loss of vision, kidney failure, cardiovascular disease, and even death. Additionally, the endothelial damage that may lead to some of these sequelae can begin soon after initiating glucocorticoid therapy. There are a number of medications available to control plasma glucose levels, the choice of which will depend on individualized monitoring of glucose levels and medication side effects. Awareness of the risk factors for developing diabetes, the signs and symptoms of the disease, and the available treatment modalities will help the practitioner in treating patients safely and effectively.

Original languageEnglish (US)
Title of host publicationBlistering Diseases: Clinical Features, Pathogenesis, Treatment
PublisherSpringer Berlin Heidelberg
Pages605-610
Number of pages6
ISBN (Print)9783662456989, 9783662456972
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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    Chapman, I., Dominguez, A. R., & Pandya, A. G. (2015). Prevention and Therapy of Steroid-Induced Diabetes. In Blistering Diseases: Clinical Features, Pathogenesis, Treatment (pp. 605-610). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-45698-9_64