TY - JOUR
T1 - Prevention of Preeclampsia - A Reality?
AU - Cunningham, F. G.
AU - Gant, N. F.
PY - 1989/8/31
Y1 - 1989/8/31
N2 - Preeclampsia and eclampsia, uniquely obstetrical complications, remain common causes of maternal and fetal morbidity and mortality. Like many other enigmatic diseases, preeclampsia has attracted over the centuries a series of treatment schemes, many of which have proved far more dangerous than the disease itself (for example, trephination and renal decapsulation). It is axiomatic that any disease can be better treated or prevented if its pathogenesis is known. This is also true of pharmacotherapy; when a drug's mechanisms of action are known, there is the promise of more rational and usually better therapeutic application. In this and an earlier issue of.
AB - Preeclampsia and eclampsia, uniquely obstetrical complications, remain common causes of maternal and fetal morbidity and mortality. Like many other enigmatic diseases, preeclampsia has attracted over the centuries a series of treatment schemes, many of which have proved far more dangerous than the disease itself (for example, trephination and renal decapsulation). It is axiomatic that any disease can be better treated or prevented if its pathogenesis is known. This is also true of pharmacotherapy; when a drug's mechanisms of action are known, there is the promise of more rational and usually better therapeutic application. In this and an earlier issue of.
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U2 - 10.1056/NEJM198908313210908
DO - 10.1056/NEJM198908313210908
M3 - Editorial
C2 - 2761603
AN - SCOPUS:0024386673
SN - 0028-4793
VL - 321
SP - 606
EP - 607
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 9
ER -