Abstract
Purpose: We determine if potassium citrate treatment stabilizes spinal bone density among patients with recurrent calcium oxalate nephrolithiasis. Materials and Methods: We studied a group of 16 men and 5 women with stones taking potassium citrate from 11 to 120 months. They represented all patients from the Stone Clinic who took potassium citrate alone for at least 11 months. L2-L4 bone mineral density data before and after potassium citrate treatment were retrieved retrospectively and analyzed. Results: In the combined group L2-L4 bone mineral density increased significantly by 3.1% over mean duration of 44 months. Z score, corrected for age matched normal values, increased significantly by 3.8%. Urinary pH, citrate and potassium increased significantly during treatment but urinary calcium did not change. Conclusions: Potassium citrate, a commonly used drug for the prevention of recurrent nephrolithiasis, may avert age dependent bone loss. Spinal bone density increased in most patients when it normally decreases.
Original language | English (US) |
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Pages (from-to) | 31-34 |
Number of pages | 4 |
Journal | Journal of Urology |
Volume | 168 |
Issue number | 1 |
DOIs | |
State | Published - 2002 |
Keywords
- Bone density
- Calculi
- Potassium citrate
ASJC Scopus subject areas
- Urology