Primary antibody and delayed type hypersensitivity response of mice to ovalbumin

Martha T. Lubet, John R. Kettman

Research output: Contribution to journalArticle

18 Scopus citations


The control of the ability to respond to three doses of ovalbumin has been studied in an attempt to find the minimum dose of antigen necessary for activation of primary antibody response and delayed type hypersensitivity response. In seven of the ten mouse strains studied, concordance of the minimum dose needed to elicit the two responses was observed. Discordance is found in the other strains, suggesting that the ability to respond to ovalbumin is independently controlled in several cells. The antibody and delayed type hypersensitivity responses to ovalbumin are controlled by at least two genes, one localized in the major histocompatibility complex.

Original languageEnglish (US)
Pages (from-to)69-79
Number of pages11
Issue number1
Publication statusPublished - Dec 1978


ASJC Scopus subject areas

  • Immunology
  • Genetics

Cite this