Primary dermatologic findings with early-onset intrahepatic cholestasis of pregnancy

Tamara T. Chao, Jeanne S. Sheffield

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background: Primary dermatologic findings are not thought to be associated with intrahepatic cholestasis of pregnancy. We report on a patient with twins who presented with a pruritic rash and cholestasis. Case: A woman with a twin gestation and two previous term stillbirths developed a pruritic rash at 16 weeks. Scleral icterus and jaundice were observed at 27 weeks. Elevated bile acid levels confirmed a diagnosis of intrahepatic cholestasis of pregnancy, and ursodeoxycholic acid therapy was initiated. Fetal heart rate decelerations were noted at 32 4/7 weeks, prompting delivery of two live male newborns. Declining laboratory values and resolution of rash occurred within a few days of delivery. Conclusion: This case illustrates an unusual presentation of recurrent cholestasis of pregnancy in a twin gestation with primary dermatologic findings.

Original languageEnglish (US)
Pages (from-to)456-458
Number of pages3
JournalObstetrics and gynecology
Volume117
Issue number2 PART 2
DOIs
StatePublished - Feb 1 2011

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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