TY - JOUR
T1 - Primary dermatologic findings with early-onset intrahepatic cholestasis of pregnancy
AU - Chao, Tamara T.
AU - Sheffield, Jeanne S.
PY - 2011/2/1
Y1 - 2011/2/1
N2 - Background: Primary dermatologic findings are not thought to be associated with intrahepatic cholestasis of pregnancy. We report on a patient with twins who presented with a pruritic rash and cholestasis. Case: A woman with a twin gestation and two previous term stillbirths developed a pruritic rash at 16 weeks. Scleral icterus and jaundice were observed at 27 weeks. Elevated bile acid levels confirmed a diagnosis of intrahepatic cholestasis of pregnancy, and ursodeoxycholic acid therapy was initiated. Fetal heart rate decelerations were noted at 32 4/7 weeks, prompting delivery of two live male newborns. Declining laboratory values and resolution of rash occurred within a few days of delivery. Conclusion: This case illustrates an unusual presentation of recurrent cholestasis of pregnancy in a twin gestation with primary dermatologic findings.
AB - Background: Primary dermatologic findings are not thought to be associated with intrahepatic cholestasis of pregnancy. We report on a patient with twins who presented with a pruritic rash and cholestasis. Case: A woman with a twin gestation and two previous term stillbirths developed a pruritic rash at 16 weeks. Scleral icterus and jaundice were observed at 27 weeks. Elevated bile acid levels confirmed a diagnosis of intrahepatic cholestasis of pregnancy, and ursodeoxycholic acid therapy was initiated. Fetal heart rate decelerations were noted at 32 4/7 weeks, prompting delivery of two live male newborns. Declining laboratory values and resolution of rash occurred within a few days of delivery. Conclusion: This case illustrates an unusual presentation of recurrent cholestasis of pregnancy in a twin gestation with primary dermatologic findings.
UR - http://www.scopus.com/inward/record.url?scp=79251574975&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79251574975&partnerID=8YFLogxK
U2 - 10.1097/AOG.0b013e3181f61b11
DO - 10.1097/AOG.0b013e3181f61b11
M3 - Article
C2 - 21252787
AN - SCOPUS:79251574975
SN - 0029-7844
VL - 117
SP - 456
EP - 458
JO - Obstetrics and gynecology
JF - Obstetrics and gynecology
IS - 2 PART 2
ER -