Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome

Fiemu E. Nwariaku; Barbra S. Miller; Richard Auchus; Shelby Holt; Lori Watumull; Bart Dolmatch; Shawna Nesbitt; Wanpen Vongpatanasin; Ronald Victor; Frank Wians; Edward Livingston; William H. Snyder; Melanie Richards; Clive S. Grant; Quan Yang Duh; Samuel Snyder; Cord Sturgeon; Thomas Biehl

doi:10.1001/archsurg.141.5.497

Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome

Fiemu E. Nwariaku, Barbra S. Miller, Richard Auchus, Shelby Holt, Lori Watumull, Bart Dolmatch, Shawna Nesbitt, Wanpen Vongpatanasin, Ronald Victor, Frank Wians, Edward Livingston, William H. Snyder, Melanie Richards, Clive S. Grant, Quan Yang Duh, Samuel Snyder, Cord Sturgeon, Thomas Biehl

Research output: Contribution to journal › Article › peer-review

136 Scopus citations

Abstract

Hypothesis: Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism. Design: Retrospective review. Setting: University medical center. Patients: Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism. Main Outcome Measures: We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes. Results: Mean±SEM adrenal nodule size was 1.54±0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia. Conclusion: Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.

Original language	English (US)
Pages (from-to)	497-503
Number of pages	7
Journal	Archives of Surgery
Volume	141
Issue number	5
DOIs	https://doi.org/10.1001/archsurg.141.5.497
State	Published - May 2006

ASJC Scopus subject areas

Surgery

Access to Document

10.1001/archsurg.141.5.497

Cite this

Nwariaku, F. E., Miller, B. S., Auchus, R., Holt, S., Watumull, L., Dolmatch, B., Nesbitt, S., Vongpatanasin, W., Victor, R., Wians, F., Livingston, E., Snyder, W. H., Richards, M., Grant, C. S., Duh, Q. Y., Snyder, S., Sturgeon, C., & Biehl, T. (2006). Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome. Archives of Surgery, 141(5), 497-503. https://doi.org/10.1001/archsurg.141.5.497

Nwariaku, FE, Miller, BS, Auchus, R, Holt, S , Watumull, L, Dolmatch, B, Nesbitt, S , Vongpatanasin, W, Victor, R, Wians, F, Livingston, E, Snyder, WH, Richards, M, Grant, CS, Duh, QY, Snyder, S, Sturgeon, C & Biehl, T 2006, 'Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome', Archives of Surgery, vol. 141, no. 5, pp. 497-503. https://doi.org/10.1001/archsurg.141.5.497

@article{4eb1af488ab24ff0865c4418af50b734,

title = "Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome",

abstract = "Hypothesis: Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism. Design: Retrospective review. Setting: University medical center. Patients: Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism. Main Outcome Measures: We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes. Results: Mean±SEM adrenal nodule size was 1.54±0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia. Conclusion: Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.",

author = "Nwariaku, {Fiemu E.} and Miller, {Barbra S.} and Richard Auchus and Shelby Holt and Lori Watumull and Bart Dolmatch and Shawna Nesbitt and Wanpen Vongpatanasin and Ronald Victor and Frank Wians and Edward Livingston and Snyder, {William H.} and Melanie Richards and Grant, {Clive S.} and Duh, {Quan Yang} and Samuel Snyder and Cord Sturgeon and Thomas Biehl",

year = "2006",

month = may,

doi = "10.1001/archsurg.141.5.497",

language = "English (US)",

volume = "141",

pages = "497--503",

journal = "Archives of Surgery",

issn = "0004-0010",

publisher = "American Medical Association",

number = "5",

}

TY - JOUR

T1 - Primary hyperaldosteronism

T2 - Effect of adrenal vein sampling on surgical outcome

AU - Nwariaku, Fiemu E.

AU - Miller, Barbra S.

AU - Auchus, Richard

AU - Holt, Shelby

AU - Watumull, Lori

AU - Dolmatch, Bart

AU - Nesbitt, Shawna

AU - Vongpatanasin, Wanpen

AU - Victor, Ronald

AU - Wians, Frank

AU - Livingston, Edward

AU - Snyder, William H.

AU - Richards, Melanie

AU - Grant, Clive S.

AU - Duh, Quan Yang

AU - Snyder, Samuel

AU - Sturgeon, Cord

AU - Biehl, Thomas

PY - 2006/5

Y1 - 2006/5

N2 - Hypothesis: Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism. Design: Retrospective review. Setting: University medical center. Patients: Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism. Main Outcome Measures: We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes. Results: Mean±SEM adrenal nodule size was 1.54±0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia. Conclusion: Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.

AB - Hypothesis: Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism. Design: Retrospective review. Setting: University medical center. Patients: Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism. Main Outcome Measures: We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes. Results: Mean±SEM adrenal nodule size was 1.54±0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia. Conclusion: Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.

UR - http://www.scopus.com/inward/record.url?scp=33646591553&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646591553&partnerID=8YFLogxK

U2 - 10.1001/archsurg.141.5.497

DO - 10.1001/archsurg.141.5.497

M3 - Article

C2 - 16702522

AN - SCOPUS:33646591553

SN - 0004-0010

VL - 141

SP - 497

EP - 503

JO - Archives of Surgery

JF - Archives of Surgery

IS - 5

ER -

Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this