Primary immune response of guinea pig spleen cells in vitro

J. Kettman, S. Ben-Sasson, J. U. Rudin

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Spleen cells of the primed guinea pig, when cultured alone, failed to make a primary immune response against heterologous erythrocytes. When supplemented with lymphocytes obtained from mineral oil induced peritoneal exudate (PEL), a primary immune response against sheep, horse and chicken RBC was obtained. The kinetics, dose response and requirement of PELs for this response are reported.

Original languageEnglish (US)
Pages (from-to)131-141
Number of pages11
JournalJournal of Immunological Methods
Volume20
Issue numberC
DOIs
StatePublished - 1978

Fingerprint

Mineral Oil
Exudates and Transudates
Horses
Chickens
Sheep
Guinea Pigs
Spleen
Erythrocytes
Lymphocytes
In Vitro Techniques

ASJC Scopus subject areas

  • Biotechnology
  • Immunology

Cite this

Primary immune response of guinea pig spleen cells in vitro. / Kettman, J.; Ben-Sasson, S.; Rudin, J. U.

In: Journal of Immunological Methods, Vol. 20, No. C, 1978, p. 131-141.

Research output: Contribution to journalArticle

Kettman, J. ; Ben-Sasson, S. ; Rudin, J. U. / Primary immune response of guinea pig spleen cells in vitro. In: Journal of Immunological Methods. 1978 ; Vol. 20, No. C. pp. 131-141.
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