Primary intramedullary melanocytoma of the spinal cord: Case report

Isaac O. Karikari; Ciaran J. Powers; Carlos A. Bagley; Thomas J. Cummings; Senthilkumar Radhakrishnan; Allan H. Friedman

doi:10.1227/01.NEU.0000341516.22126.AA

Primary intramedullary melanocytoma of the spinal cord: Case report

Isaac O. Karikari, Ciaran J. Powers, Carlos A. Bagley, Thomas J. Cummings, Senthilkumar Radhakrishnan, Allan H. Friedman

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23 Scopus citations

Abstract

OBJECTIVE: The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION: Magnetic resonance imaging of the spine, thoracic laminectomy, and histological examination revealed the diagnosis. TECHNIQUE: Microscopic and immunohistochemical analysis revealed the diagnosis of primary melanocytoma. CONCLUSION: Melanocytomas of the spine are rare lesions without distinctive imaging characteristics and pose a preoperative diagnostic challenge. A review of the relevant literature and clinical behavior of this uncommon tumor entity is provided.

Original language	English (US)
Pages (from-to)	E777-E778
Journal	Neurosurgery
Volume	64
Issue number	4
DOIs	https://doi.org/10.1227/01.NEU.0000341516.22126.AA
State	Published - Apr 2009

Keywords

Intramedullary tumor
Melanocytoma
Spinal cord

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1227/01.NEU.0000341516.22126.AA

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title = "Primary intramedullary melanocytoma of the spinal cord: Case report",

abstract = "OBJECTIVE: The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION: Magnetic resonance imaging of the spine, thoracic laminectomy, and histological examination revealed the diagnosis. TECHNIQUE: Microscopic and immunohistochemical analysis revealed the diagnosis of primary melanocytoma. CONCLUSION: Melanocytomas of the spine are rare lesions without distinctive imaging characteristics and pose a preoperative diagnostic challenge. A review of the relevant literature and clinical behavior of this uncommon tumor entity is provided.",

keywords = "Intramedullary tumor, Melanocytoma, Spinal cord",

author = "Karikari, {Isaac O.} and Powers, {Ciaran J.} and Bagley, {Carlos A.} and Cummings, {Thomas J.} and Senthilkumar Radhakrishnan and Friedman, {Allan H.}",

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language = "English (US)",

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TY - JOUR

T1 - Primary intramedullary melanocytoma of the spinal cord

T2 - Case report

AU - Karikari, Isaac O.

AU - Powers, Ciaran J.

AU - Bagley, Carlos A.

AU - Cummings, Thomas J.

AU - Radhakrishnan, Senthilkumar

AU - Friedman, Allan H.

PY - 2009/4

Y1 - 2009/4

N2 - OBJECTIVE: The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION: Magnetic resonance imaging of the spine, thoracic laminectomy, and histological examination revealed the diagnosis. TECHNIQUE: Microscopic and immunohistochemical analysis revealed the diagnosis of primary melanocytoma. CONCLUSION: Melanocytomas of the spine are rare lesions without distinctive imaging characteristics and pose a preoperative diagnostic challenge. A review of the relevant literature and clinical behavior of this uncommon tumor entity is provided.

AB - OBJECTIVE: The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION: Magnetic resonance imaging of the spine, thoracic laminectomy, and histological examination revealed the diagnosis. TECHNIQUE: Microscopic and immunohistochemical analysis revealed the diagnosis of primary melanocytoma. CONCLUSION: Melanocytomas of the spine are rare lesions without distinctive imaging characteristics and pose a preoperative diagnostic challenge. A review of the relevant literature and clinical behavior of this uncommon tumor entity is provided.

KW - Intramedullary tumor

KW - Melanocytoma

KW - Spinal cord

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Primary intramedullary melanocytoma of the spinal cord: Case report

Abstract

Keywords

ASJC Scopus subject areas

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