Primary structural analysis of the Tla region gene products, QA-2 and TL

Mark J. Soloski, Katherine R. McIntyre, Jonathan W. Uhr, Ellen S. Vitetta

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The Tla region on the murine 17th chromosome encodes at least three gene products (Qa-1, Qa-2 and TL) which are structurally similar to the major transplantation antigens H-2K, -D and -L. In this communication we compare the tryptic peptides of two Tla region-encoded gene products, Qa-2 and TL. The results indicate that TL and Qa-2 may be only modestly related in amino acid sequence and support the previous suggestion that distinct subfamilies of class I gene products with unique biochemical and functional properties may exist.

Original languageEnglish (US)
Pages (from-to)1193-1197
Number of pages5
JournalMolecular Immunology
Volume19
Issue number9
DOIs
StatePublished - 1982

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MHC Class I Genes
Histocompatibility Antigens
Genes
Amino Acid Sequence
Chromosomes
Peptides

ASJC Scopus subject areas

  • Molecular Biology
  • Immunology

Cite this

Primary structural analysis of the Tla region gene products, QA-2 and TL. / Soloski, Mark J.; McIntyre, Katherine R.; Uhr, Jonathan W.; Vitetta, Ellen S.

In: Molecular Immunology, Vol. 19, No. 9, 1982, p. 1193-1197.

Research output: Contribution to journalArticle

Soloski, Mark J. ; McIntyre, Katherine R. ; Uhr, Jonathan W. ; Vitetta, Ellen S. / Primary structural analysis of the Tla region gene products, QA-2 and TL. In: Molecular Immunology. 1982 ; Vol. 19, No. 9. pp. 1193-1197.
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