Abstract
Raman spectroscopy is used to study low-wave-number (≤ 20 cm -1) acoustic vibrations of the M13 phage. A well-defined Raman line is observed at around 8.5 cm-1. The experimental results are compared with theoretical calculations based on an elastic continuum model and appropriate Raman selection rules derived from a bond polarizability model. The observed Raman mode is shown to belong to one of the Raman-active axial modes of the M13 phage protein coat. It is expected that the detection and characterization of this low-frequency vibrational mode can be used for applications in biomedical nanotechnology such as for monitoring the process of virus functionalization and self-assembly.
Original language | English (US) |
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Article number | 024009 |
Journal | Journal of biomedical optics |
Volume | 12 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2007 |
Externally published | Yes |
Keywords
- Laser applications
- Laser spectroscopy
- Lasers in medicine
- Raman effect
- Raman spectroscopy
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Biomedical Engineering