Prodrug strategy to achieve lyophilizable, high drug loading Micelle formulations through diester derivatives of β-lapachone

Xinpeng Ma, Xiumei Huang, Gang Huang, Longshan Li, Yiguang Wang, Xiuquan Luo, David A. Boothman, Jinming Gao

Research output: Contribution to journalArticle

15 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)1210-1216
Number of pages7
JournalAdvanced healthcare materials
Volume3
Issue number8
DOIs
StatePublished - 2014

Fingerprint

Dicumarol
NAD(P)H Dehydrogenase (Quinone)
Naphthoquinones
Polylysine
Prodrugs
Micelles
Esters
Derivatives
Pharmaceutical Preparations
beta-lapachone

Keywords

  • Cancer nanomedicine
  • Diester prodrug
  • Enzyme activation
  • Polymeric micelles
  • β-lapachone

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Pharmaceutical Science
  • Medicine(all)

Cite this

Prodrug strategy to achieve lyophilizable, high drug loading Micelle formulations through diester derivatives of β-lapachone. / Ma, Xinpeng; Huang, Xiumei; Huang, Gang; Li, Longshan; Wang, Yiguang; Luo, Xiuquan; Boothman, David A.; Gao, Jinming.

In: Advanced healthcare materials, Vol. 3, No. 8, 2014, p. 1210-1216.

Research output: Contribution to journalArticle

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keywords = "Cancer nanomedicine, Diester prodrug, Enzyme activation, Polymeric micelles, β-lapachone",
author = "Xinpeng Ma and Xiumei Huang and Gang Huang and Longshan Li and Yiguang Wang and Xiuquan Luo and Boothman, {David A.} and Jinming Gao",
year = "2014",
doi = "10.1002/adhm.201300590",
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AU - Huang, Xiumei

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AU - Li, Longshan

AU - Wang, Yiguang

AU - Luo, Xiuquan

AU - Boothman, David A.

AU - Gao, Jinming

PY - 2014

Y1 - 2014

KW - Cancer nanomedicine

KW - Diester prodrug

KW - Enzyme activation

KW - Polymeric micelles

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DO - 10.1002/adhm.201300590

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