TY - JOUR
T1 - Production and applications of copper-64 radiopharmaceuticals
AU - Sun, Xiankai
AU - Anderson, Carolyn J.
PY - 2004
Y1 - 2004
N2 - The goal of this chapter is to discuss the production and applications of copper radionuclides in nuclear medicine. The interest in copper radionuclides for PET imaging and targeted radiotherapy of cancer, particularly the use of 64Cu, is increasing. Copper-64 has attractive decay properties for PET imaging and therapy, and can be used in a wide variety of applications. This chapter provides information related to the production of the radionuclides, the radiochemistry for labeling them to chelators and chelator-biomolecule conjugates, and also describes the biologic methods for evaluating compounds as radiopharmaceuticals.
AB - The goal of this chapter is to discuss the production and applications of copper radionuclides in nuclear medicine. The interest in copper radionuclides for PET imaging and targeted radiotherapy of cancer, particularly the use of 64Cu, is increasing. Copper-64 has attractive decay properties for PET imaging and therapy, and can be used in a wide variety of applications. This chapter provides information related to the production of the radionuclides, the radiochemistry for labeling them to chelators and chelator-biomolecule conjugates, and also describes the biologic methods for evaluating compounds as radiopharmaceuticals.
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U2 - 10.1016/S0076-6879(04)86011-7
DO - 10.1016/S0076-6879(04)86011-7
M3 - Article
C2 - 15120255
AN - SCOPUS:2442651865
SN - 0076-6879
VL - 386
SP - 237
EP - 261
JO - Methods in Enzymology
JF - Methods in Enzymology
ER -