Production and applications of copper-64 radiopharmaceuticals

Xiankai Sun, Carolyn J. Anderson

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The goal of this chapter is to discuss the production and applications of copper radionuclides in nuclear medicine. The interest in copper radionuclides for PET imaging and targeted radiotherapy of cancer, particularly the use of 64Cu, is increasing. Copper-64 has attractive decay properties for PET imaging and therapy, and can be used in a wide variety of applications. This chapter provides information related to the production of the radionuclides, the radiochemistry for labeling them to chelators and chelator-biomolecule conjugates, and also describes the biologic methods for evaluating compounds as radiopharmaceuticals.

Original languageEnglish (US)
Pages (from-to)237-261
Number of pages25
JournalMethods in Enzymology
Volume386
DOIs
StatePublished - 2004

Fingerprint

Radiopharmaceuticals
Radioisotopes
Copper
Chelating Agents
Radiochemistry
Nuclear medicine
Imaging techniques
Nuclear Medicine
Radiotherapy
Biomolecules
Radionuclide Imaging
Labeling
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Biochemistry

Cite this

Production and applications of copper-64 radiopharmaceuticals. / Sun, Xiankai; Anderson, Carolyn J.

In: Methods in Enzymology, Vol. 386, 2004, p. 237-261.

Research output: Contribution to journalArticle

Sun, Xiankai ; Anderson, Carolyn J. / Production and applications of copper-64 radiopharmaceuticals. In: Methods in Enzymology. 2004 ; Vol. 386. pp. 237-261.
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