Previous studies have established the beneficial effects of naloxone in reducing the severity of neurologic dysfunction in animals subjected to traumatic spinal cord injury or spinal stroke (1). In the present study, rabbits treated with naloxone had significantly improved neurologic outcomes following temporary aortic occlusion. This suggests that opiate antagonists may be useful in protecting high-risk patients from surgical post-aortic cross-clamping paraplegia.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Jan 1 1985|
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