Prospects for the commercialization of chemiluminescence-based point-of-care and on-site testing devices

Jason Y. Park, Larry J. Kricka

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Chemiluminescent reactions have found application in a number of commercial point-of-care and on-site testing devices. Notable examples include allergy tests (e.g., MASTpette, OPTIGEN® systems), flu tests (e.g., ZstatFlu®-II), cartridge-based immunoassay systems (FastPack® IP System, PATHFAST®), forensic tests for bloodstains, portable analyzers for biochip array assays (Evidence MultiStat), water quality tests (Eclox), air pollutants (e.g., oxides of nitrogen), and handheld devices for detecting explosives (e.g., E3500 Chemilux®). Many other point-of-care or on-site testing devices with a chemiluminescent end point have been devised on the basis of a variety of formats (e.g., cuvette, cassette, dipstick, test strip, microchip), but most have not progressed beyond a proof-of-principle or prototype stage.

Original languageEnglish (US)
Pages (from-to)5631-5637
Number of pages7
JournalAnalytical and Bioanalytical Chemistry
Volume406
Issue number23
StatePublished - Sep 1 2014

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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