TY - GEN
T1 - Prostate cancer detection based on three dimensional sonoelastography
AU - Castaneda, B.
AU - Hoyt, K.
AU - Zhang, M.
AU - Pasternack, D.
AU - Baxter, L.
AU - Nigwekar, P.
AU - Di Sant'Agnese, A.
AU - Joseph, J.
AU - Strang, J.
AU - Rubens, D. J.
AU - Parker, K. J.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - In this paper, we evaluate the performance of sonoelastography for prostate cancer detection. Ultrasound (US) B-mode and sonoelastographic volumes were acquired from five prostate glands ex vivo. Additionally, one more gland was imaged in vivo using a transrectal US probe. Semi-automatic algorithms were used to segment the surface of the gland from the B-mode volume and the tumors from sonoelastographic data. To assess the detection performance, three dimensional (3D) sonoelastographic findings were compared in size and position to 3D histological data. Sonoelastography detected seven out of nine cancers in the ex vivo prostate glands and two out of three malignant masses in the in vivo experiment. Overall, 3D sonoelastography has shown potential for prostate cancer detection albeit based on limited data.
AB - In this paper, we evaluate the performance of sonoelastography for prostate cancer detection. Ultrasound (US) B-mode and sonoelastographic volumes were acquired from five prostate glands ex vivo. Additionally, one more gland was imaged in vivo using a transrectal US probe. Semi-automatic algorithms were used to segment the surface of the gland from the B-mode volume and the tumors from sonoelastographic data. To assess the detection performance, three dimensional (3D) sonoelastographic findings were compared in size and position to 3D histological data. Sonoelastography detected seven out of nine cancers in the ex vivo prostate glands and two out of three malignant masses in the in vivo experiment. Overall, 3D sonoelastography has shown potential for prostate cancer detection albeit based on limited data.
KW - Elasticity imaging
KW - Prostate cancer detection
KW - Three-dimensional sonoelastography
UR - http://www.scopus.com/inward/record.url?scp=48149083274&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=48149083274&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2007.340
DO - 10.1109/ULTSYM.2007.340
M3 - Conference contribution
AN - SCOPUS:48149083274
SN - 1424413834
SN - 9781424413836
T3 - Proceedings - IEEE Ultrasonics Symposium
SP - 1353
EP - 1356
BT - 2007 IEEE Ultrasonics Symposium Proceedings, IUS
T2 - 2007 IEEE Ultrasonics Symposium, IUS
Y2 - 28 October 2007 through 31 October 2007
ER -