TY - JOUR
T1 - Prostatic urethral lift
T2 - Two-year results after treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia
AU - Chin, Peter T.
AU - Bolton, Damien M.
AU - Jack, Greg
AU - Rashid, Prem
AU - Thavaseelan, Jeffrey
AU - Yu, R. James
AU - Roehrborn, Claus
AU - Woo, Henry H.
N1 - Funding Information:
Funding Support: This study was funded by NeoTract, Inc.
Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/1
Y1 - 2012/1
N2 - To evaluate the effectiveness of the prostatic urethral lift in relieving lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia. A total of 64 men, aged >55 years, with moderate to severe symptomatic benign prostatic hyperplasia were treated and followed up at 6 Australian institutions. The treatment consisted of transurethral delivery of small implants to secure the prostatic lobes in an open condition, thereby reducing obstruction of the urethral lumen. The effectiveness, including International Prostate Symptom Score, quality of life, benign prostatic hyperplasia Impact Index, and peak urethral flow rate were assessed at 2 weeks and 3, 6, 12, and 24 months. The effect of this treatment on erectile and ejaculatory function was assessed using the Sexual Health Inventory for Men and Male Sexual Health Questionnaire for Ejaculatory Dysfunction. The prostatic urethral lift improved LUTS symptoms rapidly and durably. The International Prostate Symptom Score was reduced 42% at 2 weeks, 49% at 6 months, and 42% at 2 years in evaluable patients. The peak flow rate improved by >30% (2.4 mL/s) at all intervals compared with baseline. No compromise in sexual function was observed after this treatment. The present study demonstrated that LUTS and flow improvements without compromising sexual function. Although this was an early study with a small cohort, this therapy shows promise as a new option for patients with LUTS.
AB - To evaluate the effectiveness of the prostatic urethral lift in relieving lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia. A total of 64 men, aged >55 years, with moderate to severe symptomatic benign prostatic hyperplasia were treated and followed up at 6 Australian institutions. The treatment consisted of transurethral delivery of small implants to secure the prostatic lobes in an open condition, thereby reducing obstruction of the urethral lumen. The effectiveness, including International Prostate Symptom Score, quality of life, benign prostatic hyperplasia Impact Index, and peak urethral flow rate were assessed at 2 weeks and 3, 6, 12, and 24 months. The effect of this treatment on erectile and ejaculatory function was assessed using the Sexual Health Inventory for Men and Male Sexual Health Questionnaire for Ejaculatory Dysfunction. The prostatic urethral lift improved LUTS symptoms rapidly and durably. The International Prostate Symptom Score was reduced 42% at 2 weeks, 49% at 6 months, and 42% at 2 years in evaluable patients. The peak flow rate improved by >30% (2.4 mL/s) at all intervals compared with baseline. No compromise in sexual function was observed after this treatment. The present study demonstrated that LUTS and flow improvements without compromising sexual function. Although this was an early study with a small cohort, this therapy shows promise as a new option for patients with LUTS.
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U2 - 10.1016/j.urology.2011.10.021
DO - 10.1016/j.urology.2011.10.021
M3 - Article
C2 - 22202539
AN - SCOPUS:84555178562
SN - 0090-4295
VL - 79
SP - 5
EP - 11
JO - Urology
JF - Urology
IS - 1
ER -