Proton translocating ATPases: Issues in structure and function

D. K. Stone, X. S. Xie

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

In this general overview of a new class of electrogenic proton translocating ATPases, assembled evidence indicates that these proton pumps are distant ancestors of classic F1F0 type ATPases. As pointed out, definition of the precise mechanisms by which these proton pumps in general, and the renal proton pump(s) in particular operate and are regulated awaits considerable work. Resolution of certain key issues, notably endomembrane H+ ATPase microheterogeneity, molecular structure and cellular regulation are likely to result in implications pertinent not only to renal physiology, but also to basic issues in cellular and molecular biology.

Original languageEnglish (US)
Pages (from-to)767-774
Number of pages8
JournalKidney International
Volume33
Issue number4
StatePublished - 1988

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Proton Pumps
Proton-Translocating ATPases
Kidney
Molecular Structure
Cell Biology
Adenosine Triphosphatases
Molecular Biology

ASJC Scopus subject areas

  • Nephrology

Cite this

Proton translocating ATPases : Issues in structure and function. / Stone, D. K.; Xie, X. S.

In: Kidney International, Vol. 33, No. 4, 1988, p. 767-774.

Research output: Contribution to journalArticle

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