Pseudo-outbreak of Mycobacterium fortuitum on a human immunodeficiency virus ward: Transient respiratory tract colonization from a contaminated ice machine

Kelly A. Gebo, Arjun Srinivasan, Trish M. Perl, Tracy Ross, Amy Groth, William G. Merz

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Infection Control surveillance revealed an abnormally high number of sputum samples growing Mycobacterium fortuitum from a single ward that houses the human immunodeficiency virus service. We investigated the outbreak using a retrospective case-control study and molecular epidemiology. A total of 47 patients were identified with ≥ 1 sputum sample that grew M. fortuitum. No significant demographic or clinical variables were found to be associated with colonization. Environmental investigation demonstrated that the M. fortuitum isolated from patients was identical to the ice machine isolates by pulsed-field gel electrophoresis. Fortunately, there has been no evidence of progressive pulmonary disease developing in our patients after ≥6 months of follow-up. All cases were thought to represent transient colonization and not infection. The ice machine was disconnected and cleaned successfully with vinegar and then bleach. Only when a 0.5-μm filter was installed were no further patients colonized or water cultures found to be positive.

Original languageEnglish (US)
Pages (from-to)32-38
Number of pages7
JournalClinical Infectious Diseases
Volume35
Issue number1
DOIs
StatePublished - Jul 1 2002

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Mycobacterium fortuitum
Ice
Respiratory System
Disease Outbreaks
HIV
Sputum
Molecular Epidemiology
Pulsed Field Gel Electrophoresis
Infection Control
Acetic Acid
Lung Diseases
Case-Control Studies
Demography
Water
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Pseudo-outbreak of Mycobacterium fortuitum on a human immunodeficiency virus ward : Transient respiratory tract colonization from a contaminated ice machine. / Gebo, Kelly A.; Srinivasan, Arjun; Perl, Trish M.; Ross, Tracy; Groth, Amy; Merz, William G.

In: Clinical Infectious Diseases, Vol. 35, No. 1, 01.07.2002, p. 32-38.

Research output: Contribution to journalArticle

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