Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis

Whitney A. High, Mai P. Hoang, Paul R. Bergstresser

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Papulosquamous eruptions involving the palms and soles are thought to be particularly suggestive of secondary syphilis. Alternative diagnoses exist, however, and include psoriasis guttata, atypical pityriasis rosea, and pityriasis lichenoides chronica (PLC). We describe the case of a patient with an abrupt onset of psoriasis guttata and extensive palmoplantar involvement. Results of serologic testing were negative for treponemicidal antibodies. Results of histopathologic examination demonstrated psoriasiform dermatitis with neutrophils in the epidermis; plasma cells were absent. Spirochetes were not demonstrated in a tissue sample using silver or immunohistochemical stains for Treponema pallidum. A broad differential diagnosis is required when evaluating papulosquamous eruptions with palmoplantar involvement. Although not well referenced in the medical literature, psoriasis guttata can indeed cause palmoplantar lesions that mimic those of secondary syphilis.

Original languageEnglish (US)
Pages (from-to)358-360
Number of pages3
JournalCutis
Volume76
Issue number6
StatePublished - Dec 2005

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Psoriasis
Pityriasis Lichenoides
Pityriasis Rosea
Treponema pallidum
Spirochaetales
Dermatitis
Plasma Cells
Silver
Epidermis
Neutrophils
Differential Diagnosis
Coloring Agents
Antibodies
Secondary syphilis

ASJC Scopus subject areas

  • Dermatology
  • Immunology and Allergy

Cite this

High, W. A., Hoang, M. P., & Bergstresser, P. R. (2005). Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis. Cutis, 76(6), 358-360.

Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis. / High, Whitney A.; Hoang, Mai P.; Bergstresser, Paul R.

In: Cutis, Vol. 76, No. 6, 12.2005, p. 358-360.

Research output: Contribution to journalArticle

High, WA, Hoang, MP & Bergstresser, PR 2005, 'Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis', Cutis, vol. 76, no. 6, pp. 358-360.
High WA, Hoang MP, Bergstresser PR. Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis. Cutis. 2005 Dec;76(6):358-360.
High, Whitney A. ; Hoang, Mai P. ; Bergstresser, Paul R. / Psoriasis guttata with palmoplantar involvement clinically mimicking secondary syphilis. In: Cutis. 2005 ; Vol. 76, No. 6. pp. 358-360.
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