PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts

Medicine & Life Sciences

• Protein Deficiency 100%
• Phosphoprotein Phosphatases 89%
• Metabolic Bone Diseases 83%
• Proline 81%
• Osteoclasts 79%
• Protein Phosphatase 2 66%
• Mouse Pstpip2 protein 41%
• Macrophage Colony-Stimulating Factor Receptors 38%
• Extramedullary Hematopoiesis 24%
• pexidartinib 16%
• Osteogenesis 14%
• 2-tyrosine 13%
• Myelopoiesis 12%
• Bone and Bones 10%
• Inflammation 10%
• Missense Mutation 8%
• Myeloid Cells 8%
• Phosphoric Monoester Hydrolases 8%
• Macrophages 5%
• Phosphorylation 5%
• Mutation 4%
• Skin 4%
• Serum 3%
• In Vitro Techniques 3%
• Proteins 3%
• Therapeutics 1%

Chemical Compounds

• Threonine 85%
• Proline 78%
• Serine 71%
• Protein 31%
• Mutation 11%
• Serum Level 9%
• Tyrosine 6%
• Probe 4%