Pulmonary 3 T MRI with ultrashort TEs: Influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers

Yoshiharu Ohno, Mizuho Nishio, Hisanobu Koyama, Takeshi Yoshikawa, Sumiaki Matsumoto, Shinichiro Seki, Makoto Obara, Marc Van Cauteren, Masaya Takahashi, Kazuro Sugimura

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Purpose To assess the influence of ultrashort TE (UTE) intervals on pulmonary magnetic resonance imaging (MRI) with UTEs (UTE-MRI) for pulmonary functional loss assessment and clinical stage classification of smokers. Materials and Methods A total 60 consecutive smokers (43 men and 17 women; mean age 70 years) with and without COPD underwent thin-section multidetector row computed tomography (MDCT), UTE-MRI, and pulmonary functional measurements. For each smoker, UTE-MRI was performed with three different UTE intervals (UTE-MRI A: 0.5 msec, UTE-MRI B: 1.0 msec, UTE-MRI C: 1.5 msec). By using the GOLD guidelines, the subjects were classified as: "smokers without COPD," "mild COPD," "moderate COPD," and "severe or very severe COPD." Then the mean T2* value from each UTE-MRI and CT-based functional lung volume (FLV) were correlated with pulmonary function test. Finally, Fisher's PLSD test was used to evaluate differences in each index among the four clinical stages. Results Each index correlated significantly with pulmonary function test results (P < 0.05). CT-based FLV and mean T2* values obtained from UTE-MRI A and B showed significant differences among all groups except between "smokers without COPD" and "mild COPD" groups (P < 0.05). Conclusion UTE-MRI has a potential for management of smokers and the UTE interval is suggested as an important parameter in this setting.

Original languageEnglish (US)
Pages (from-to)988-997
Number of pages10
JournalJournal of Magnetic Resonance Imaging
Volume39
Issue number4
DOIs
StatePublished - 2014

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Magnetic Resonance Imaging
Chronic Obstructive Pulmonary Disease
Lung
Respiratory Function Tests
Multidetector Computed Tomography
Guidelines

Keywords

  • COPD
  • CT
  • lung
  • magnetic resonance
  • pulmonary emphysema
  • ultrashort echo time

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Pulmonary 3 T MRI with ultrashort TEs : Influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers. / Ohno, Yoshiharu; Nishio, Mizuho; Koyama, Hisanobu; Yoshikawa, Takeshi; Matsumoto, Sumiaki; Seki, Shinichiro; Obara, Makoto; Van Cauteren, Marc; Takahashi, Masaya; Sugimura, Kazuro.

In: Journal of Magnetic Resonance Imaging, Vol. 39, No. 4, 2014, p. 988-997.

Research output: Contribution to journalArticle

Ohno, Y, Nishio, M, Koyama, H, Yoshikawa, T, Matsumoto, S, Seki, S, Obara, M, Van Cauteren, M, Takahashi, M & Sugimura, K 2014, 'Pulmonary 3 T MRI with ultrashort TEs: Influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers', Journal of Magnetic Resonance Imaging, vol. 39, no. 4, pp. 988-997. https://doi.org/10.1002/jmri.24232
Ohno, Yoshiharu ; Nishio, Mizuho ; Koyama, Hisanobu ; Yoshikawa, Takeshi ; Matsumoto, Sumiaki ; Seki, Shinichiro ; Obara, Makoto ; Van Cauteren, Marc ; Takahashi, Masaya ; Sugimura, Kazuro. / Pulmonary 3 T MRI with ultrashort TEs : Influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers. In: Journal of Magnetic Resonance Imaging. 2014 ; Vol. 39, No. 4. pp. 988-997.
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abstract = "Purpose To assess the influence of ultrashort TE (UTE) intervals on pulmonary magnetic resonance imaging (MRI) with UTEs (UTE-MRI) for pulmonary functional loss assessment and clinical stage classification of smokers. Materials and Methods A total 60 consecutive smokers (43 men and 17 women; mean age 70 years) with and without COPD underwent thin-section multidetector row computed tomography (MDCT), UTE-MRI, and pulmonary functional measurements. For each smoker, UTE-MRI was performed with three different UTE intervals (UTE-MRI A: 0.5 msec, UTE-MRI B: 1.0 msec, UTE-MRI C: 1.5 msec). By using the GOLD guidelines, the subjects were classified as: {"}smokers without COPD,{"} {"}mild COPD,{"} {"}moderate COPD,{"} and {"}severe or very severe COPD.{"} Then the mean T2* value from each UTE-MRI and CT-based functional lung volume (FLV) were correlated with pulmonary function test. Finally, Fisher's PLSD test was used to evaluate differences in each index among the four clinical stages. Results Each index correlated significantly with pulmonary function test results (P < 0.05). CT-based FLV and mean T2* values obtained from UTE-MRI A and B showed significant differences among all groups except between {"}smokers without COPD{"} and {"}mild COPD{"} groups (P < 0.05). Conclusion UTE-MRI has a potential for management of smokers and the UTE interval is suggested as an important parameter in this setting.",
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T2 - Influence of ultrashort echo time interval on pulmonary functional and clinical stage assessments of smokers

AU - Ohno, Yoshiharu

AU - Nishio, Mizuho

AU - Koyama, Hisanobu

AU - Yoshikawa, Takeshi

AU - Matsumoto, Sumiaki

AU - Seki, Shinichiro

AU - Obara, Makoto

AU - Van Cauteren, Marc

AU - Takahashi, Masaya

AU - Sugimura, Kazuro

PY - 2014

Y1 - 2014

N2 - Purpose To assess the influence of ultrashort TE (UTE) intervals on pulmonary magnetic resonance imaging (MRI) with UTEs (UTE-MRI) for pulmonary functional loss assessment and clinical stage classification of smokers. Materials and Methods A total 60 consecutive smokers (43 men and 17 women; mean age 70 years) with and without COPD underwent thin-section multidetector row computed tomography (MDCT), UTE-MRI, and pulmonary functional measurements. For each smoker, UTE-MRI was performed with three different UTE intervals (UTE-MRI A: 0.5 msec, UTE-MRI B: 1.0 msec, UTE-MRI C: 1.5 msec). By using the GOLD guidelines, the subjects were classified as: "smokers without COPD," "mild COPD," "moderate COPD," and "severe or very severe COPD." Then the mean T2* value from each UTE-MRI and CT-based functional lung volume (FLV) were correlated with pulmonary function test. Finally, Fisher's PLSD test was used to evaluate differences in each index among the four clinical stages. Results Each index correlated significantly with pulmonary function test results (P < 0.05). CT-based FLV and mean T2* values obtained from UTE-MRI A and B showed significant differences among all groups except between "smokers without COPD" and "mild COPD" groups (P < 0.05). Conclusion UTE-MRI has a potential for management of smokers and the UTE interval is suggested as an important parameter in this setting.

AB - Purpose To assess the influence of ultrashort TE (UTE) intervals on pulmonary magnetic resonance imaging (MRI) with UTEs (UTE-MRI) for pulmonary functional loss assessment and clinical stage classification of smokers. Materials and Methods A total 60 consecutive smokers (43 men and 17 women; mean age 70 years) with and without COPD underwent thin-section multidetector row computed tomography (MDCT), UTE-MRI, and pulmonary functional measurements. For each smoker, UTE-MRI was performed with three different UTE intervals (UTE-MRI A: 0.5 msec, UTE-MRI B: 1.0 msec, UTE-MRI C: 1.5 msec). By using the GOLD guidelines, the subjects were classified as: "smokers without COPD," "mild COPD," "moderate COPD," and "severe or very severe COPD." Then the mean T2* value from each UTE-MRI and CT-based functional lung volume (FLV) were correlated with pulmonary function test. Finally, Fisher's PLSD test was used to evaluate differences in each index among the four clinical stages. Results Each index correlated significantly with pulmonary function test results (P < 0.05). CT-based FLV and mean T2* values obtained from UTE-MRI A and B showed significant differences among all groups except between "smokers without COPD" and "mild COPD" groups (P < 0.05). Conclusion UTE-MRI has a potential for management of smokers and the UTE interval is suggested as an important parameter in this setting.

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KW - CT

KW - lung

KW - magnetic resonance

KW - pulmonary emphysema

KW - ultrashort echo time

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