Pulmonary emphysema

Current concepts of pathogenesis

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Pulmonary emphysema is a major public health problem and is primarily a disease of smokers. The pathogenesis of emphysema in smokers is likely to be multifactorial and may involve protease-antiprotease imbalance, abnormal host response to injury, the inactivation of antiproteases by oxidants, and direct damage of lung tissue by pulmonary phagocytes. The data regarding current concepts of pathogenesis of emphysema in smokers are reviewed in this article.

Original languageEnglish (US)
Pages (from-to)125-138
Number of pages14
JournalAmerican Journal of the Medical Sciences
Volume293
Issue number2
StatePublished - 1987

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Pulmonary Emphysema
Emphysema
Protease Inhibitors
Lung
Phagocytes
Oxidants
Peptide Hydrolases
Public Health
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pulmonary emphysema : Current concepts of pathogenesis. / Weissler, J. C.

In: American Journal of the Medical Sciences, Vol. 293, No. 2, 1987, p. 125-138.

Research output: Contribution to journalArticle

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