Doença pulmonar em pacientes com artrite reumatoide: Avaliação radiográfica e espirométrica

Translated title of the contribution: Pulmonary involvement in rheumatoid arthritis: Evaluation by radiography and spirometry

Alexandre de Melo Kawassaki, Daniel Antunes Silva Pereira, Fernando Uliana Kay, Ieda Maria Magalhães Laurindo, Carlos Roberto Ribeiro Carvalho, Ronaldo Adib Kairalla

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: To determine whether simple diagnostic methods can yield relevant disease information in patients with rheumatoid arthritis (RA). Methods: Patients with RA were randomly selected for inclusion in a cross-sectional study involving clinical evaluation of pulmonary function, including pulse oximetry (determination of SpO2, at rest), chest X-ray, and spirometry. Results: A total of 246 RA patients underwent complete assessments. Half of the patients in our sample reported a history of smoking. Spirometry was abnormal in 30% of the patients; the chest X-ray was abnormal in 45%; and the SpO2 was abnormal in 13%. Normal chest X-ray, spirometry, and SpO2 were observed simultaneously in only 41% of the RA patients. A history of smoking was associated with abnormal spirometry findings, including evidence of obstructive or restrictive lung disease, and with abnormal chest X-ray findings, as well as with an interstitial pattern on the chest X-ray. Comparing the patients in whom all test results were normal (n = 101) with those in whom abnormal test results were obtained (n = 145), we found a statistically significant difference between the two groups, in terms of age and smoking status. Notably, there were signs of airway disease in nearly half of the patients with minimal or no history of tobacco smoke exposure. Conclusions: Pulmonary involvement in RA can be identified through the use of a combination of diagnostic methods that are simple, safe, and inexpensive. Our results lead us to suggest that RA patients with signs of lung involvement should be screened for lung abnormalities, even if presenting with no respiratory symptoms.

Original languagePortuguese
Pages (from-to)331-342
Number of pages12
JournalJornal Brasileiro de Pneumologia
Volume41
Issue number4
DOIs
StatePublished - Jan 1 2015

Fingerprint

Spirometry
Radiography
Rheumatoid Arthritis
Lung
Thorax
X-Rays
Smoking
Oximetry
Smoke
Lung Diseases
Tobacco
Cross-Sectional Studies

Keywords

  • Airway obstruction
  • Arthritis
  • Interstitial
  • Lung diseases
  • Radiography
  • Rheumatoid
  • Spirometry
  • Thoracic

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Kawassaki, A. D. M., Pereira, D. A. S., Kay, F. U., Laurindo, I. M. M., Carvalho, C. R. R., & Kairalla, R. A. (2015). Doença pulmonar em pacientes com artrite reumatoide: Avaliação radiográfica e espirométrica. Jornal Brasileiro de Pneumologia, 41(4), 331-342. https://doi.org/10.1590/S1806-37132015000004518

Doença pulmonar em pacientes com artrite reumatoide : Avaliação radiográfica e espirométrica. / Kawassaki, Alexandre de Melo; Pereira, Daniel Antunes Silva; Kay, Fernando Uliana; Laurindo, Ieda Maria Magalhães; Carvalho, Carlos Roberto Ribeiro; Kairalla, Ronaldo Adib.

In: Jornal Brasileiro de Pneumologia, Vol. 41, No. 4, 01.01.2015, p. 331-342.

Research output: Contribution to journalArticle

Kawassaki, Alexandre de Melo ; Pereira, Daniel Antunes Silva ; Kay, Fernando Uliana ; Laurindo, Ieda Maria Magalhães ; Carvalho, Carlos Roberto Ribeiro ; Kairalla, Ronaldo Adib. / Doença pulmonar em pacientes com artrite reumatoide : Avaliação radiográfica e espirométrica. In: Jornal Brasileiro de Pneumologia. 2015 ; Vol. 41, No. 4. pp. 331-342.
@article{1ed199c3420e48c4a1e96eeb4476d221,
title = "Doen{\cc}a pulmonar em pacientes com artrite reumatoide: Avalia{\cc}{\~a}o radiogr{\'a}fica e espirom{\'e}trica",
abstract = "Objective: To determine whether simple diagnostic methods can yield relevant disease information in patients with rheumatoid arthritis (RA). Methods: Patients with RA were randomly selected for inclusion in a cross-sectional study involving clinical evaluation of pulmonary function, including pulse oximetry (determination of SpO2, at rest), chest X-ray, and spirometry. Results: A total of 246 RA patients underwent complete assessments. Half of the patients in our sample reported a history of smoking. Spirometry was abnormal in 30{\%} of the patients; the chest X-ray was abnormal in 45{\%}; and the SpO2 was abnormal in 13{\%}. Normal chest X-ray, spirometry, and SpO2 were observed simultaneously in only 41{\%} of the RA patients. A history of smoking was associated with abnormal spirometry findings, including evidence of obstructive or restrictive lung disease, and with abnormal chest X-ray findings, as well as with an interstitial pattern on the chest X-ray. Comparing the patients in whom all test results were normal (n = 101) with those in whom abnormal test results were obtained (n = 145), we found a statistically significant difference between the two groups, in terms of age and smoking status. Notably, there were signs of airway disease in nearly half of the patients with minimal or no history of tobacco smoke exposure. Conclusions: Pulmonary involvement in RA can be identified through the use of a combination of diagnostic methods that are simple, safe, and inexpensive. Our results lead us to suggest that RA patients with signs of lung involvement should be screened for lung abnormalities, even if presenting with no respiratory symptoms.",
keywords = "Airway obstruction, Arthritis, Interstitial, Lung diseases, Radiography, Rheumatoid, Spirometry, Thoracic",
author = "Kawassaki, {Alexandre de Melo} and Pereira, {Daniel Antunes Silva} and Kay, {Fernando Uliana} and Laurindo, {Ieda Maria Magalh{\~a}es} and Carvalho, {Carlos Roberto Ribeiro} and Kairalla, {Ronaldo Adib}",
year = "2015",
month = "1",
day = "1",
doi = "10.1590/S1806-37132015000004518",
language = "Portuguese",
volume = "41",
pages = "331--342",
journal = "Jornal Brasileiro de Pneumologia",
issn = "1806-3713",
publisher = "Sociedade Brasileira de Pneumologia e Tisiologia",
number = "4",

}

TY - JOUR

T1 - Doença pulmonar em pacientes com artrite reumatoide

T2 - Avaliação radiográfica e espirométrica

AU - Kawassaki, Alexandre de Melo

AU - Pereira, Daniel Antunes Silva

AU - Kay, Fernando Uliana

AU - Laurindo, Ieda Maria Magalhães

AU - Carvalho, Carlos Roberto Ribeiro

AU - Kairalla, Ronaldo Adib

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Objective: To determine whether simple diagnostic methods can yield relevant disease information in patients with rheumatoid arthritis (RA). Methods: Patients with RA were randomly selected for inclusion in a cross-sectional study involving clinical evaluation of pulmonary function, including pulse oximetry (determination of SpO2, at rest), chest X-ray, and spirometry. Results: A total of 246 RA patients underwent complete assessments. Half of the patients in our sample reported a history of smoking. Spirometry was abnormal in 30% of the patients; the chest X-ray was abnormal in 45%; and the SpO2 was abnormal in 13%. Normal chest X-ray, spirometry, and SpO2 were observed simultaneously in only 41% of the RA patients. A history of smoking was associated with abnormal spirometry findings, including evidence of obstructive or restrictive lung disease, and with abnormal chest X-ray findings, as well as with an interstitial pattern on the chest X-ray. Comparing the patients in whom all test results were normal (n = 101) with those in whom abnormal test results were obtained (n = 145), we found a statistically significant difference between the two groups, in terms of age and smoking status. Notably, there were signs of airway disease in nearly half of the patients with minimal or no history of tobacco smoke exposure. Conclusions: Pulmonary involvement in RA can be identified through the use of a combination of diagnostic methods that are simple, safe, and inexpensive. Our results lead us to suggest that RA patients with signs of lung involvement should be screened for lung abnormalities, even if presenting with no respiratory symptoms.

AB - Objective: To determine whether simple diagnostic methods can yield relevant disease information in patients with rheumatoid arthritis (RA). Methods: Patients with RA were randomly selected for inclusion in a cross-sectional study involving clinical evaluation of pulmonary function, including pulse oximetry (determination of SpO2, at rest), chest X-ray, and spirometry. Results: A total of 246 RA patients underwent complete assessments. Half of the patients in our sample reported a history of smoking. Spirometry was abnormal in 30% of the patients; the chest X-ray was abnormal in 45%; and the SpO2 was abnormal in 13%. Normal chest X-ray, spirometry, and SpO2 were observed simultaneously in only 41% of the RA patients. A history of smoking was associated with abnormal spirometry findings, including evidence of obstructive or restrictive lung disease, and with abnormal chest X-ray findings, as well as with an interstitial pattern on the chest X-ray. Comparing the patients in whom all test results were normal (n = 101) with those in whom abnormal test results were obtained (n = 145), we found a statistically significant difference between the two groups, in terms of age and smoking status. Notably, there were signs of airway disease in nearly half of the patients with minimal or no history of tobacco smoke exposure. Conclusions: Pulmonary involvement in RA can be identified through the use of a combination of diagnostic methods that are simple, safe, and inexpensive. Our results lead us to suggest that RA patients with signs of lung involvement should be screened for lung abnormalities, even if presenting with no respiratory symptoms.

KW - Airway obstruction

KW - Arthritis

KW - Interstitial

KW - Lung diseases

KW - Radiography

KW - Rheumatoid

KW - Spirometry

KW - Thoracic

UR - http://www.scopus.com/inward/record.url?scp=84941887957&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941887957&partnerID=8YFLogxK

U2 - 10.1590/S1806-37132015000004518

DO - 10.1590/S1806-37132015000004518

M3 - Article

C2 - 26398753

AN - SCOPUS:84941887957

VL - 41

SP - 331

EP - 342

JO - Jornal Brasileiro de Pneumologia

JF - Jornal Brasileiro de Pneumologia

SN - 1806-3713

IS - 4

ER -