Pulmonary vascular underperfusion score in premature infants with bronchopulmonary dysplasia and pulmonary hypertension

Bibhuti B. Das, Michelle Marie Jadotte, Kak Chen Chan

Research output: Contribution to journalArticle


Pulmonary hypertension (PH) is a complication of bronchopulmonary dysplasia (BPD). The underlying pathophysiology of BPD-associated PH is complex and poorly understood. Echocardiogram may underestimate the severity of pulmonary hypertensive vascular disease in severe BPD. Digital subtraction pulmonary angiography (DSPA) is a potentially useful imaging modality for evaluating changes in the pulmonary vasculature of BPD-associated PH. In this study, we objectively quantified the pulmonary hypertensive vascular changes demonstrated by DSPA using a novel pulmonary vascular underperfusion score (PVUS) and correlated the scoring system with echocardiography parameters and cardiac hemodynamics by right heart catheterization.

Original languageEnglish (US)
Article number359
JournalMedicina (Lithuania)
Issue number7
Publication statusPublished - Jan 1 2019
Externally publishedYes



  • Bronchopulmonary dysplasia
  • Digital subtraction pulmonary angiography
  • Premature infant
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Medicine(all)

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