Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis

Medicine & Life Sciences

• Erythropoiesis 81%
• Erythropoietin 73%
• Yeasts 56%
• Erythropoietin Receptors 14%
• Animal Models 7%
• Erythroid Precursor Cells 6%
• Pichia 6%
• Thalassemia 6%
• Sickle Cell Anemia 5%
• Amino Acid Substitution 5%
• Alanine 5%
• Arginine 4%
• Bone Marrow 3%
• Apoptosis 3%
• Mutation 2%
• Growth 2%
• Pharmaceutical Preparations 2%

Chemical Compounds

• Erythropoietin 100%
• Purification 47%
• Homodimer 5%
• Arginine 5%
• Alanine 4%
• Mutation 4%
• Block Like Crystal 3%
• Substitution Reaction 3%
• Drug 2%
• Acid 1%