QSAR prediction of HIV inhibition activity of styrylquinoline derivatives by genetic algorithm coupled with multiple linear regressions

Medicine & Life Sciences

• styrylquinoline 100%
• Quantitative Structure-Activity Relationship 64%
• Linear Models 37%
• HIV 32%
• p31 integrase protein, Human immunodeficiency virus 1 18%
• Drug-Related Side Effects and Adverse Reactions 10%
• Drug Resistance 10%
• HIV-1 10%
• Antiviral Agents 10%
• Drug Therapy 6%
• In Vitro Techniques 5%
• Therapeutics 1%

Chemical Compounds

• Styrylquinoline 83%
• QSAR Study 48%
• Compound Derivative 15%
• Non Toxic 12%
• Bioactivity 8%
• Block Like Crystal 7%
• Molecule 4%