QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli

Regan M. Russell, Faith C. Sharp, David A. Rasko, Vanessa Sperandio

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded regulator QseA. This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners.

Original languageEnglish (US)
Pages (from-to)5387-5392
Number of pages6
JournalJournal of bacteriology
Volume189
Issue number14
DOIs
StatePublished - Jul 1 2007

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ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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