QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli

Regan M. Russell; Faith C. Sharp; David A. Rasko; Vanessa Sperandio

doi:10.1128/JB.00553-07

QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli

Regan M. Russell, Faith C. Sharp, David A. Rasko, Vanessa Sperandio

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded regulator QseA. This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners.

Original language	English (US)
Pages (from-to)	5387-5392
Number of pages	6
Journal	Journal of bacteriology
Volume	189
Issue number	14
DOIs	https://doi.org/10.1128/JB.00553-07
State	Published - Jul 2007

ASJC Scopus subject areas

Microbiology
Molecular Biology

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abstract = "Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded regulator QseA. This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners.",

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QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli

Abstract

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