QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli

Regan M. Russell, Faith C. Sharp, David A. Rasko, Vanessa Sperandio

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded regulator QseA. This work demonstrates that GrlR/GrlA activate LEE2 transcription in a Ler-independent fashion, whereas transcription of grlRA is activated by QseA in both Ler-dependent and -independent manners.

Original languageEnglish (US)
Pages (from-to)5387-5392
Number of pages6
JournalJournal of Bacteriology
Volume189
Issue number14
DOIs
StatePublished - Jul 2007

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Enterohemorrhagic Escherichia coli
Enterocytes
Genes
Proteins

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

Cite this

QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli. / Russell, Regan M.; Sharp, Faith C.; Rasko, David A.; Sperandio, Vanessa.

In: Journal of Bacteriology, Vol. 189, No. 14, 07.2007, p. 5387-5392.

Research output: Contribution to journalArticle

Russell, Regan M. ; Sharp, Faith C. ; Rasko, David A. ; Sperandio, Vanessa. / QseA and GrlR/GrlA regulation of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli. In: Journal of Bacteriology. 2007 ; Vol. 189, No. 14. pp. 5387-5392.
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