Quantification of vaginal support: Are continuous summary scores better than POPQ stage?

Linda Brubaker, Matthew D. Barber, Ingrid Nygaard, Charlie W. Nager, Edward Varner, Joseph Schaffer, Anthony Visco, Susan Meikle, Cathie Spino

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Objective This analysis compared 3 continuous variables as summary support loss (SL) scores with pelvic organ prolapse (POP) quantification (POPQ) ordinal stages. Study Design We used pooled baseline data from 1141 subjects in 3 randomized trials (CARE, n = 322; OPUS, n = 380; ATLAS, n = 439) to test 3 SL measures. The relative responsiveness was assessed using the standardized response mean of 2-year outcome data from the CARE trial. Results Each SL measure was strongly correlated with POPQ ordinal staging; the single most distal POPQ point had the strongest correlation. Improvements in anatomic support were weakly correlated with improvements in POP Distress Inventory (r = 0.170.24; P < .01 for each) but not with changes in POP Impact Questionnaire for all measures of SL or POPQ stage. Conclusion While continuous, single number summary measures compared favorably to ordinal POPQ staging system, the single most distal POPQ point may be preferable to POPQ ordinal stages to summarize or compare group data.

Original languageEnglish (US)
Pages (from-to)512.e1-512.e6
JournalAmerican journal of obstetrics and gynecology
Volume203
Issue number5
DOIs
StatePublished - Nov 2010

Keywords

  • outcome measures
  • pelvic organ prolapse
  • pelvic surgery
  • prolapse
  • quantification of prolapse

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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    Brubaker, L., Barber, M. D., Nygaard, I., Nager, C. W., Varner, E., Schaffer, J., Visco, A., Meikle, S., & Spino, C. (2010). Quantification of vaginal support: Are continuous summary scores better than POPQ stage? American journal of obstetrics and gynecology, 203(5), 512.e1-512.e6. https://doi.org/10.1016/j.ajog.2010.06.071