Quantitation of response to therapy in calcium urolithiasis

Joseph E. Zerwekh, Olesegun Lawoyin, Charles Y C Pak

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The physico-chemical basis for the action of various drugs in calcium nephrolithiasis may be described in terms of changes produced in the urinary state of saturation (APR), limit of metastability (FPR), or in crystal growth. The validation of this scheme for drug action requires further correlation of objective responses to drug therapy, described in terms of urinary crystallisation, with the clinical response.

Original languageEnglish (US)
Pages (from-to)209-213
Number of pages5
JournalUrological Research
Issue number3
StatePublished - Sep 1 1979


  • Crystal growth
  • Metastable solutions
  • Urinary saturation
  • treatment

ASJC Scopus subject areas

  • Urology


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