Quantitative Analysis of Growth Factors from a Second Filter Using the Reamer-Irrigator-Aspirator System: Description of a Novel Technique

James P. Stannard; Ashoke K. Sathy; Fariba Moeinpour; Rena L. Stewart; David A. Volgas

doi:10.1016/j.ocl.2009.07.002

Quantitative Analysis of Growth Factors from a Second Filter Using the Reamer-Irrigator-Aspirator System: Description of a Novel Technique

James P. Stannard, Ashoke K. Sathy, Fariba Moeinpour, Rena L. Stewart, David A. Volgas

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Use of the Reamer-Irrigator-Aspirator (RIA) as a source of autogenous bone graft in the treatment of nonunions is increasing. We report on our novel technique of using a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while using the RIA system. We also quantify growth factor concentrations in the collections from the TCP filter. A second filter attached in series with the standard RIA filtration system yields TCP with substantial concentrations of bioactive proteins that are equal to those seen in the bone graft that is harvested in the first filter.

Original language	English (US)
Pages (from-to)	95-98
Number of pages	4
Journal	Orthopedic Clinics of North America
Volume	41
Issue number	1
DOIs	https://doi.org/10.1016/j.ocl.2009.07.002
State	Published - Jan 2010

Keywords

Bone grafting
Growth factors
Long bone nonunion
Reamer-Irrigator-Aspirator (RIA)
TCP filter

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.ocl.2009.07.002

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title = "Quantitative Analysis of Growth Factors from a Second Filter Using the Reamer-Irrigator-Aspirator System: Description of a Novel Technique",

abstract = "Use of the Reamer-Irrigator-Aspirator (RIA) as a source of autogenous bone graft in the treatment of nonunions is increasing. We report on our novel technique of using a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while using the RIA system. We also quantify growth factor concentrations in the collections from the TCP filter. A second filter attached in series with the standard RIA filtration system yields TCP with substantial concentrations of bioactive proteins that are equal to those seen in the bone graft that is harvested in the first filter.",

keywords = "Bone grafting, Growth factors, Long bone nonunion, Reamer-Irrigator-Aspirator (RIA), TCP filter",

author = "Stannard, {James P.} and Sathy, {Ashoke K.} and Fariba Moeinpour and Stewart, {Rena L.} and Volgas, {David A.}",

note = "Funding Information: Research funding support for this project was provided by Synthes, Inc, Paoli, PA. ",

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AU - Stannard, James P.

AU - Sathy, Ashoke K.

AU - Moeinpour, Fariba

AU - Stewart, Rena L.

AU - Volgas, David A.

N1 - Funding Information: Research funding support for this project was provided by Synthes, Inc, Paoli, PA.

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N2 - Use of the Reamer-Irrigator-Aspirator (RIA) as a source of autogenous bone graft in the treatment of nonunions is increasing. We report on our novel technique of using a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while using the RIA system. We also quantify growth factor concentrations in the collections from the TCP filter. A second filter attached in series with the standard RIA filtration system yields TCP with substantial concentrations of bioactive proteins that are equal to those seen in the bone graft that is harvested in the first filter.

AB - Use of the Reamer-Irrigator-Aspirator (RIA) as a source of autogenous bone graft in the treatment of nonunions is increasing. We report on our novel technique of using a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while using the RIA system. We also quantify growth factor concentrations in the collections from the TCP filter. A second filter attached in series with the standard RIA filtration system yields TCP with substantial concentrations of bioactive proteins that are equal to those seen in the bone graft that is harvested in the first filter.

KW - Bone grafting

KW - Growth factors

KW - Long bone nonunion

KW - Reamer-Irrigator-Aspirator (RIA)

KW - TCP filter

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Quantitative Analysis of Growth Factors from a Second Filter Using the Reamer-Irrigator-Aspirator System: Description of a Novel Technique

Abstract

Keywords

ASJC Scopus subject areas

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