Quantitative assessment of synovitis in Legg-Calvé-Perthes disease using gadolinium-enhanced MRI

David C. Neal; Jack C. O'Brien; Jamie Burgess; Chanhee Jo; Harry K W Kim

doi:10.1097/BPB.0000000000000107

Quantitative assessment of synovitis in Legg-Calvé-Perthes disease using gadolinium-enhanced MRI

David C. Neal, Jack C. O'Brien, Jamie Burgess, Chanhee Jo, Harry K W Kim

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A quantitative method to assess hip synovitis in Legg-Calvé-Perthes disease (LCPD) is not currently available. To develop this method, the areas of synovial enhancement on gadolinium-enhanced MRI (Gd-MRI) were measured by two independent observers. The volume of synovial enhancement was significantly increased in the initial and the fragmentation stages of LCPD (Waldenström stages I and II), with a persistence of synovitis into the reossification stage (stage III). The Gd-MRI method had high interobserver and intraobserver agreements and may serve as a useful method to monitor the effect of various treatments on hip synovitis in LCPD.

Original language	English (US)
Pages (from-to)	89-94
Number of pages	6
Journal	Journal of Pediatric Orthopaedics Part B
Volume	24
Issue number	2
DOIs	https://doi.org/10.1097/BPB.0000000000000107
State	Published - Mar 6 2015

Keywords

Legg-Calvé-Perthes disease
avascular necrosis
gadolinium-enhanced MRI
hip synovitis
osteonecrosis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Orthopedics and Sports Medicine

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10.1097/BPB.0000000000000107

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title = "Quantitative assessment of synovitis in Legg-Calv{\'e}-Perthes disease using gadolinium-enhanced MRI",

abstract = "A quantitative method to assess hip synovitis in Legg-Calv{\'e}-Perthes disease (LCPD) is not currently available. To develop this method, the areas of synovial enhancement on gadolinium-enhanced MRI (Gd-MRI) were measured by two independent observers. The volume of synovial enhancement was significantly increased in the initial and the fragmentation stages of LCPD (Waldenstr{\"o}m stages I and II), with a persistence of synovitis into the reossification stage (stage III). The Gd-MRI method had high interobserver and intraobserver agreements and may serve as a useful method to monitor the effect of various treatments on hip synovitis in LCPD.",

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AU - O'Brien, Jack C.

AU - Burgess, Jamie

AU - Jo, Chanhee

AU - Kim, Harry K W

PY - 2015/3/6

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AB - A quantitative method to assess hip synovitis in Legg-Calvé-Perthes disease (LCPD) is not currently available. To develop this method, the areas of synovial enhancement on gadolinium-enhanced MRI (Gd-MRI) were measured by two independent observers. The volume of synovial enhancement was significantly increased in the initial and the fragmentation stages of LCPD (Waldenström stages I and II), with a persistence of synovitis into the reossification stage (stage III). The Gd-MRI method had high interobserver and intraobserver agreements and may serve as a useful method to monitor the effect of various treatments on hip synovitis in LCPD.

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KW - avascular necrosis

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KW - osteonecrosis

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Quantitative assessment of synovitis in Legg-Calvé-Perthes disease using gadolinium-enhanced MRI

Abstract

Keywords

ASJC Scopus subject areas

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