Quantitative assessment of tumor oxygen dynamics: Molecular imaging for prognostic radiology

Ralph P. Mason, Sophia Ran, Philip E. Thorpe

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

One of the fundamental molecules governing the survival of mammalian cells is oxygen. Oxygen has gained particular significance in tumor developmental biology and oncology. An increasingly diverse array of methods is now available to characterize tumor oxygenation. This Prospect will consider a new method, Fluorocarbon Relaxometry using Echo planar imaging for Dynamic Oxygen Mapping (FREDOM), which we have recently developed for oximetry, examine application to a specific therapeutic example and place this technique in the context of other approaches.

Original languageEnglish (US)
Pages (from-to)45-53
Number of pages9
JournalJournal of Cellular Biochemistry
Issue numberSUPPL. 39
DOIs
StatePublished - 2002

Keywords

  • Antibody targeting
  • Hexafluorobenzene
  • Magnetic resonance imaging
  • Oxygen
  • Tissue factor
  • Tumor

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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