Quantitative mass spectrometry as a tool for nutritional proteomics

James J. Moresco, Meng Qiu Dong, John R. Yates

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

The goal of nutritional science is to determine the effect of dietary components. Proteomics has emerged as a method to study proteins on a large scale. The proteomic information gathered from a sample, whether a biological fluid, cell, or tissue, includes not only the identities of proteins present but also their quantities and posttranslational modifications. Recent advances in mass spectrometry make it possible to accurately measure concentrations of thousands of proteins derived from such complex biological samples. Quantitative data will provide increased understanding of the dynamic changes in the proteome induced by dietary components.

Original languageEnglish (US)
Pages (from-to)597-604
Number of pages8
JournalAmerican Journal of Clinical Nutrition
Volume88
Issue number3
DOIs
StatePublished - Sep 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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