Radiation for Hodgkin's lymphoma in young female patients: A new technique to avoid the breasts and decrease the dose to the heart

Bouthaina S. Dabaja, Neal C S Rebueno, Ali Mazloom, Scott Thorne, Kelly J. Perrin, Naresh Tolani, Pragnan Das, Marc E. Delclos, Puneeth Iyengar, Valerie K. Reed, Patrecia Horace, Mohammad R. Salehpour

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Purpose: To demonstrate how, in young female patients with Hodgkin's lymphoma, using an inclined board technique can further decrease the volume of breasts and heart in the treatment field. Methods and Materials: An inclined board was constructed with the ability to mount an Aquaplast face mask, a Vacu-Lock, and a hip stopper. Eight female patients with early-stage Hodgkin's lymphoma were planned and compared using the conventional flat position and the inclined board position. All patients on the inclined board were planned with 90° degree table position and 15° gantry angle rotation to compensate for the beam divergence resulting from the patient's position on the inclined board. Dose-volume histograms were generated, as well as the mean V30 and V5 of both breasts and heart using both treatment positions. Results: The mean value of V30 of the right breast, left breast, and heart decreased from 3%, 3%, and 13%, respectively, using the flat position to 0, 0.4%, and 5%, respectively, using the inclined board. The mean value of V5 of the right breast, left breast, and heart decreased from 6%, 13%, and 36%, respectively, using the flat position to 2%, 8%, and 29%, respectively, using the inclined board. Conclusions: Compared with conventional flat positioning, this simple device and technique allows better sparing of the breasts and the heart while maintaining comparable target coverage and total lung dose.

Original languageEnglish (US)
Pages (from-to)503-507
Number of pages5
JournalInternational Journal of Radiation Oncology Biology Physics
Volume79
Issue number2
DOIs
StatePublished - Feb 1 2011

Keywords

  • Breast
  • Female
  • Hodgkin's
  • Lymphoma
  • Radiation

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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    Dabaja, B. S., Rebueno, N. C. S., Mazloom, A., Thorne, S., Perrin, K. J., Tolani, N., Das, P., Delclos, M. E., Iyengar, P., Reed, V. K., Horace, P., & Salehpour, M. R. (2011). Radiation for Hodgkin's lymphoma in young female patients: A new technique to avoid the breasts and decrease the dose to the heart. International Journal of Radiation Oncology Biology Physics, 79(2), 503-507. https://doi.org/10.1016/j.ijrobp.2009.11.013