Radiolabeling and in vitro and in vivo characterization of [ ¹⁸F]FB-[R^8,15,21, L¹⁷]-VIP as a PET imaging agent for tumor overexpressed VIP receptors

Chemical Compounds

• Vasoactive Intestinal Peptide 100%
• Fluorobenzoate 38%
• IC50 30%
• Radiopharmaceutical 26%
• Prosthetic Group 26%
• Radiochemical Yield 26%
• Positron 25%
• Peptide 25%
• Clearance 23%
• Radioactivity 21%
• Purity 10%

Medicine & Life Sciences

• Vasoactive Intestinal Peptide Receptors 99%
• In Vitro Techniques 28%
• N-succinimidyl-4-fluorobenzoate 25%
• Peptides 24%
• Neoplasms 21%
• Radiopharmaceuticals 15%
• Vasoactive Intestinal Peptide 15%
• Autoradiography 13%
• Radioactivity 12%
• Positron-Emission Tomography 12%
• Inhibitory Concentration 50 11%
• Colorectal Neoplasms 10%
• Muscles 7%
• Membranes 7%
• Lung 6%