TY - JOUR
T1 - Radiologically guided percutaneous fine-needle aspiration biopsy of pelvic and retroperitoneal masses
T2 - A retrospective study of 68 cases
AU - Guo, Ziwen
AU - Kurtycz, Daniel F.I.
AU - De Las Casas, Luis E.
AU - Hoerl, H. Daniel
PY - 2001
Y1 - 2001
N2 - Fine-needle aspiration (FNA) of the pelvis and retroperitoneum (excluding the pancreas, kidney, and adrenal masses) has not achieved its full potential as a diagnostic modality. We reviewed 68 percutaneous, radiologically guided FNAs from these locations to assess the clinical utility and complication rate of this procedure. Satisfactory' material was obtained in 66 cases (97.1%), of which 37 were deemed positive (55%), 3 suspicious (4%), 4 atypical (6%), and 22 negative (32%) for malignancy; two cases (3%) were unsatisfactory. Compared to biopsy (36 patients) and clinical information, the sensitivity and specificity of FNA for malignancy were 90.2% and 100%, respectively, yielding a positive predictive value of 100% and a negative predictive value of 86.6%. The four false-negative cases (5.9%) were due to sampling error. One patient had a minor complication (hematoma) from the procedure. We conclude that FNA is the procedure of choice for detecting most malignancies in these two locations.
AB - Fine-needle aspiration (FNA) of the pelvis and retroperitoneum (excluding the pancreas, kidney, and adrenal masses) has not achieved its full potential as a diagnostic modality. We reviewed 68 percutaneous, radiologically guided FNAs from these locations to assess the clinical utility and complication rate of this procedure. Satisfactory' material was obtained in 66 cases (97.1%), of which 37 were deemed positive (55%), 3 suspicious (4%), 4 atypical (6%), and 22 negative (32%) for malignancy; two cases (3%) were unsatisfactory. Compared to biopsy (36 patients) and clinical information, the sensitivity and specificity of FNA for malignancy were 90.2% and 100%, respectively, yielding a positive predictive value of 100% and a negative predictive value of 86.6%. The four false-negative cases (5.9%) were due to sampling error. One patient had a minor complication (hematoma) from the procedure. We conclude that FNA is the procedure of choice for detecting most malignancies in these two locations.
KW - Deep-seated lesions
KW - Fine-needle aspiration
KW - Pelvis
KW - Radiologic guidance
KW - Retroperitoneurn
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U2 - 10.1002/dc.2000
DO - 10.1002/dc.2000
M3 - Article
C2 - 11466812
AN - SCOPUS:0034931976
SN - 8755-1039
VL - 25
SP - 43
EP - 49
JO - Diagnostic cytopathology
JF - Diagnostic cytopathology
IS - 1
ER -