Radioresistance of cells responsible for delayed hypersensitivity reactions in the mouse

J. Kettman, M. C. Mathews

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The cells responsible for delayed hypersensitivity reactivity in the mouse act in a radioresistant fashion only if such irradiated cells are injected directly into the site of antigen challenge. Intravenous transfer of irradiated, primed spleen cells does not achieve a transfer of sensitivity to show delayed type hypersensitivity reactions. Transfer of sensitivity by the intravenous route can be effected by injection of non irradiated spleen cells from primed mice.

Original languageEnglish (US)
Pages (from-to)606-608
Number of pages3
JournalJournal of Immunology
Volume115
Issue number2
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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