The cells responsible for delayed hypersensitivity reactivity in the mouse act in a radioresistant fashion only if such irradiated cells are injected directly into the site of antigen challenge. Intravenous transfer of irradiated, primed spleen cells does not achieve a transfer of sensitivity to show delayed type hypersensitivity reactions. Transfer of sensitivity by the intravenous route can be effected by injection of non irradiated spleen cells from primed mice.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Immunology|
|State||Published - Dec 1 1975|
ASJC Scopus subject areas
- Immunology and Allergy