Random versus targeted biopsies for colorectal cancer surveillance in inflammatory bowel disease

Tasneem Ahmed, Jennifer Monti, Bret Lashner

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

For many years, cancer surveillance colonoscopy in ulcerative colitis patients has involved obtaining at least 30 biopsies of flat and abnormal-appearing mucosa. With the advent of better imaging techniques, biopsies can be better targeted to abnormal-appearing mucosa, thereby increasing the sensitivity of testing. Use of chromoendoscopy, narrow-band imaging, autofluorescence, or confocal endomicroscopy to target biopsies is likely to improve detection of dysplasia and identification of patients at high risk for developing cancer.

Original languageEnglish (US)
Pages (from-to)438-442
Number of pages5
JournalGastroenterology and Hepatology
Volume6
Issue number7
StatePublished - Jul 1 2010

Keywords

  • Autofluorescence
  • Cancer surveillance
  • Chromoendoscopy
  • Confocal endomicroscopy
  • Narrow-band imaging
  • Random versus targeted biopsies
  • Ulcerative colitis

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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