RAPID DIAGNOSIS OF TUBERCULOUS MENINGITIS BY LATEX PARTICLE AGGLUTINATION

Elias Krambovitis, PaulE Lock, MichaelB Mcillmurray, William Hendrickse, Helen Holzel

Research output: Contribution to journalArticle

90 Scopus citations

Abstract

A simple latex particle agglutination test for the rapid detection of Mycobacteriumtuberculosis plasma membrane antigen in cerebrospinal fluid was evaluated in 18 children with tuberculous meningitis and 134 control children with other disorders. The antigen was detected in all 18 patients with tuberculous meningitis, although an initial sample from 1 patient did not contain detectable antigen before it was concentrated. 133 of 134 control samples gave negative results.

Original languageEnglish (US)
Pages (from-to)1229-1231
Number of pages3
JournalThe Lancet
Volume324
Issue number8414
DOIs
StatePublished - Dec 1 1984

ASJC Scopus subject areas

  • Medicine(all)

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    Krambovitis, E., Lock, P., Mcillmurray, M., Hendrickse, W., & Holzel, H. (1984). RAPID DIAGNOSIS OF TUBERCULOUS MENINGITIS BY LATEX PARTICLE AGGLUTINATION. The Lancet, 324(8414), 1229-1231. https://doi.org/10.1016/S0140-6736(84)92792-2