Rapid Relief of Anxiety in Cancer Patients With Both Alprazolam and Placebo

T. G. Wald, R. G. Kathol, R. Noyes, B. T. Carroll, G. H. Clamon

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

This study evaluated 36 cancer patients who were enrolled in a randomized, double-blind, placebo-controlled trial conducted over a 4-week period to evaluate the efficacy of alprazolam in the treatment of anxiety associated with cancer. Hamilton Anxiety Scale scores declined significantly between baseline and the end of the first week of the study in both treatment groups. There was no significant difference in response between the patients receiving alprazolam and placebo. Similar results were obtained from other instruments. These results suggest that nondrug factors or spontaneous improvement may play a more important role than pharmacotherapy in the treatment of anxiety associated with cancer.

Original languageEnglish (US)
Pages (from-to)324-332
Number of pages9
JournalPsychosomatics
Volume34
Issue number4
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Applied Psychology
  • Psychiatry and Mental health

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